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KCNJ8 potassium inwardly rectifying channel subfamily J member 8 [ Canis lupus familiaris (dog) ]

Gene ID: 486639, updated on 25-Jul-2026
Official Symbol
KCNJ8provided by VGNC
Official Full Name
potassium inwardly rectifying channel subfamily J member 8provided by VGNC
Primary source
VGNC:VGNC:42268
See related
Ensembl:ENSCAFG00845014663 RGD:12388503
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See KCNJ8 in Genome Data Viewer
Location:
chromosome: 27
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (25588424..25595600)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (20985001..20992186, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (21155847..21163033, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (25386897..25394078)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (25410445..25417631)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene cytidine monophosphate N-acetylneuraminic acid synthetase Neighboring gene ATP binding cassette subfamily C member 9 Neighboring gene lactate dehydrogenase B Neighboring gene glycogen synthase 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. ATP sensitive K(+) channels are critical for maintaining myocardial perfusion and high energy phosphates in the failing heart. Jameel MN, et al. J Mol Cell Cardiol, 2016 Mar. PMID 26854629, Free PMC Article
  2. Persistent beneficial effect of postconditioning against infarct size: role of mitochondrial K(ATP) channels during reperfusion. Mykytenko J, et al. Basic Res Cardiol, 2008 Sep. PMID 18600365
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Thus, in the failing heart the balance between myocardial ATP demands and oxygen delivery is critically dependent on functioning KATP channels.
    Title: ATP sensitive K(+) channels are critical for maintaining myocardial perfusion and high energy phosphates in the failing heart.
  2. cardioprotection in myocardial infarct is achieved in postconditioning my opening the KATP)channel during reperfusion
    Title: Persistent beneficial effect of postconditioning against infarct size: role of mitochondrial K(ATP) channels during reperfusion.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-activated inward rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
ATP-sensitive inward rectifier potassium channel 8
Names
potassium voltage-gated channel subfamily J member 8

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    25588424..25595600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038438789.1 → XP_038294717.1  ATP-sensitive inward rectifier potassium channel 8

    UniProtKB/TrEMBL
    A0A8C0K4Y8, A0A8I3NUB2
    Related
    ENSCAFP00845020677.1, ENSCAFT00845026229.1
    Conserved Domains (2) summary
    pfam01007
    Location:37 → 184
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:191 → 363
    IRK_C; Inward rectifier potassium channel C-terminal domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    25386897..25394078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038513461.1 → XP_038369389.1  

    Conserved Domains (2) summary
    pfam01007
    Location:37 → 184
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:191 → 363
    IRK_C; Inward rectifier potassium channel C-terminal domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    25410445..25417631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038641260.1 → XP_038497188.1  

    Conserved Domains (2) summary
    pfam01007
    Location:37 → 184
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:191 → 363
    IRK_C; Inward rectifier potassium channel C-terminal domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    21155847..21163033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577015.1 → XP_038432943.1  ATP-sensitive inward rectifier potassium channel 8

    UniProtKB/TrEMBL
    A0A8C0K4Y8, A0A8I3NUB2
    Conserved Domains (2) summary
    pfam01007
    Location:37 → 184
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:191 → 363
    IRK_C; Inward rectifier potassium channel C-terminal domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    20985001..20992186 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014108709.3 → XP_013964184.1  ATP-sensitive inward rectifier potassium channel 8

    UniProtKB/TrEMBL
    A0A8C0K4Y8, A0A8I3NUB2
    Conserved Domains (2) summary
    pfam01007
    Location:37 → 184
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:191 → 363
    IRK_C; Inward rectifier potassium channel C-terminal domain
Nucleotide Protein
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