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RACGAP1 Rac GTPase activating protein 1 [ Canis lupus familiaris (dog) ]

Gene ID: 486549, updated on 27-Jun-2026
Official Symbol
RACGAP1provided by VGNC
Official Full Name
Rac GTPase activating protein 1provided by VGNC
Primary source
VGNC:VGNC:45308
See related
Ensembl:ENSCAFG00845017966 RGD:12186343
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See RACGAP1 in Genome Data Viewer
Location:
chromosome: 27
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (4737980..4766051)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (41541242..41569279, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (41935897..41964171, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (4702991..4731034)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (4692808..4720859)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866368 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Neighboring gene acid sensing ion channel subunit 1 Neighboring gene uncharacterized LOC111092823 Neighboring gene aquaporin 6 Neighboring gene aquaporin 5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
rac GTPase-activating protein 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    4737980..4766051
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038438224.1 → XP_038294152.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  2. XM_038438228.1 → XP_038294156.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  3. XM_038438223.1 → XP_038294151.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Related
    ENSCAFP00845024997.1, ENSCAFT00845031965.1
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  4. XM_038438226.1 → XP_038294154.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  5. XM_038438225.1 → XP_038294153.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  6. XM_038438227.1 → XP_038294155.1  rac GTPase-activating protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KNV2
    Conserved Domains (2) summary
    cd04382
    Location:253 → 446
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    cd20821
    Location:192 → 245
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    4702991..4731034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038512926.1 → XP_038368854.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  2. XM_038512930.1 → XP_038368858.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  3. XM_038512924.1 → XP_038368852.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  4. XM_038512928.1 → XP_038368856.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  5. XM_038512927.1 → XP_038368855.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  6. XM_038512929.1 → XP_038368857.1  

    Conserved Domains (2) summary
    cd04382
    Location:253 → 446
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    cd20821
    Location:192 → 245
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    4692808..4720859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038640697.1 → XP_038496625.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  2. XM_038640701.1 → XP_038496629.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  3. XM_038640696.1 → XP_038496624.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  4. XM_038640699.1 → XP_038496627.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  5. XM_038640698.1 → XP_038496626.1  

    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  6. XM_038640700.1 → XP_038496628.1  

    Conserved Domains (2) summary
    cd04382
    Location:253 → 446
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    cd20821
    Location:192 → 245
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    41935897..41964171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577615.1 → XP_038433543.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNV2

  2. XM_038577613.1 → XP_038433541.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNV2

  3. XM_038577614.1 → XP_038433542.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNV2

  4. XM_038577617.1 → XP_038433545.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNV2

  5. XM_038577616.1 → XP_038433544.1  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNV2

  6. XM_038577618.1 → XP_038433546.1  rac GTPase-activating protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KNV2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41541242..41569279 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005636864.3 → XP_005636921.2  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  2. XM_005636863.4 → XP_005636920.2  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  3. XM_005636865.4 → XP_005636922.2  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  4. XM_543675.7 → XP_543675.3  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  5. XM_022411182.2 → XP_022266890.2  rac GTPase-activating protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63
    Conserved Domains (3) summary
    cd04382
    Location:346 → 539
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    TIGR02168
    Location:13 → 105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd20821
    Location:285 → 338
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

  6. XM_014108730.3 → XP_013964205.2  rac GTPase-activating protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KNV2
    Conserved Domains (2) summary
    cd04382
    Location:253 → 446
    RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
    cd20821
    Location:192 → 245
    C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
Nucleotide Protein
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