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RNF185 ring finger protein 185 [ Canis lupus familiaris (dog) ]

Gene ID: 486362, updated on 25-Jul-2026
Official Symbol
RNF185provided by VGNC
Official Full Name
ring finger protein 185provided by VGNC
Primary source
VGNC:VGNC:45648
See related
Ensembl:ENSCAFG00845022335 RGD:12283247
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See RNF185 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (24528662..24562031)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (24016013..24048667)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (24555332..24588724)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (24232140..24265067)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (24494085..24527022)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene selenoprotein M Neighboring gene inositol polyphosphate-5-phosphatase J Neighboring gene phospholipase A2 group III Neighboring gene uncharacterized LOC111092639 Neighboring gene LIM domain kinase 2 Neighboring gene uncharacterized LOC106557828 Neighboring gene phosphoinositide-3-kinase interacting protein 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-like protein conjugating enzyme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein ligase RNF185

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    24528662..24562031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038437291.1 → XP_038293219.1  E3 ubiquitin-protein ligase RNF185 isoform X1

    Conserved Domains (2) summary
    PLN03208
    Location:138 → 174
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:128 → 142
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_038437292.1 → XP_038293220.1  E3 ubiquitin-protein ligase RNF185 isoform X2

    Conserved Domains (2) summary
    PLN03208
    Location:121 → 157
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:110 → 125
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_038437293.1 → XP_038293221.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Related
    ENSCAFP00845031079.1, ENSCAFT00845039671.1
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  4. XM_038437297.1 → XP_038293225.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  5. XM_038437294.1 → XP_038293222.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  6. XM_038437296.1 → XP_038293224.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  7. XM_038437298.1 → XP_038293226.1  E3 ubiquitin-protein ligase RNF185 isoform X4

    Conserved Domains (2) summary
    PLN03208
    Location:46 → 82
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:36 → 50
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  8. XM_038437295.1 → XP_038293223.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    24232140..24265067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038512189.1 → XP_038368117.1  

    Conserved Domains (2) summary
    PLN03208
    Location:138 → 174
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:128 → 142
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_038512190.1 → XP_038368118.1  

    Conserved Domains (2) summary
    PLN03208
    Location:121 → 157
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:110 → 125
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_038512191.1 → XP_038368119.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  4. XM_038512194.1 → XP_038368122.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  5. XM_038512192.1 → XP_038368120.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  6. XM_038512193.1 → XP_038368121.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  7. XM_038512195.1 → XP_038368123.1  

    Conserved Domains (2) summary
    PLN03208
    Location:46 → 82
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:36 → 50
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    24494085..24527022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038639885.1 → XP_038495813.1  

    Conserved Domains (2) summary
    PLN03208
    Location:138 → 174
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:128 → 142
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_038639886.1 → XP_038495814.1  

    Conserved Domains (2) summary
    PLN03208
    Location:121 → 157
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:110 → 125
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_038639887.1 → XP_038495815.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  4. XM_038639891.1 → XP_038495819.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  5. XM_038639888.1 → XP_038495816.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  6. XM_038639890.1 → XP_038495818.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  7. XM_038639892.1 → XP_038495820.1  

    Conserved Domains (2) summary
    PLN03208
    Location:46 → 82
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:36 → 50
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  8. XM_038639889.1 → XP_038495817.1  

    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    24555332..24588724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038575690.1 → XP_038431618.1  E3 ubiquitin-protein ligase RNF185 isoform X1

    Conserved Domains (2) summary
    PLN03208
    Location:138 → 174
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:128 → 142
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_038575691.1 → XP_038431619.1  E3 ubiquitin-protein ligase RNF185 isoform X2

    Conserved Domains (2) summary
    PLN03208
    Location:121 → 157
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:110 → 125
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_038575692.1 → XP_038431620.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  4. XM_038575696.1 → XP_038431624.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  5. XM_038575693.1 → XP_038431621.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  6. XM_038575695.1 → XP_038431623.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  7. XM_038575697.1 → XP_038431625.1  E3 ubiquitin-protein ligase RNF185 isoform X4

    Conserved Domains (2) summary
    PLN03208
    Location:46 → 82
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:36 → 50
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  8. XM_038575694.1 → XP_038431622.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    24016013..24048667
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038459194.1 → XP_038315122.1  E3 ubiquitin-protein ligase RNF185 isoform X1

    Conserved Domains (2) summary
    PLN03208
    Location:138 → 174
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:128 → 142
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_038459195.1 → XP_038315123.1  E3 ubiquitin-protein ligase RNF185 isoform X2

    Conserved Domains (2) summary
    PLN03208
    Location:121 → 157
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:110 → 125
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_005636464.4 → XP_005636521.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    See identical proteins and their annotated locations for XP_005636521.1

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  4. XM_847541.6 → XP_852634.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    See identical proteins and their annotated locations for XP_852634.1

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  5. XM_022410630.2 → XP_022266338.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  6. XM_022410632.2 → XP_022266340.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins

  7. XM_038459196.1 → XP_038315124.1  E3 ubiquitin-protein ligase RNF185 isoform X4

    Conserved Domains (2) summary
    PLN03208
    Location:46 → 82
    PLN03208; E3 ubiquitin-protein ligase RMA2; Provisional
    cl17238
    Location:36 → 50
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  8. XM_022410631.2 → XP_022266339.1  E3 ubiquitin-protein ligase RNF185 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTD3, A0A8I3S346
    Conserved Domains (1) summary
    cd16744
    Location:38 → 80
    RING-HC_RNF185; RING finger, HC subclass, found in RING finger protein 185 (RNF185) and similar proteins
Nucleotide Protein
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