Format

Send to:

Choose Destination

NPAT nuclear protein, coactivator of histone transcription [ Homo sapiens (human) ]

Gene ID: 4863, updated on 5-Aug-2018
Official Symbol
NPATprovided by HGNC
Official Full Name
nuclear protein, coactivator of histone transcriptionprovided by HGNC
Primary source
HGNC:HGNC:7896
See related
Ensembl:ENSG00000149308 MIM:601448; Vega:OTTHUMG00000166385
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
E14; p220; E14/NPAT
Expression
Ubiquitous expression in lymph node (RPKM 6.0), spleen (RPKM 3.9) and 25 other tissues See more
Orthologs
See NPAT in Genome Data Viewer
Location:
11q22.3
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 11 NC_000011.10 (108155280..108222638, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (108028117..108093365, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene cullin 5 Neighboring gene acetyl-CoA acetyltransferase 1 Neighboring gene ATM serine/threonine kinase Neighboring gene chromosome 11 open reading frame 65 Neighboring gene KDEL motif containing 2

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein C-terminus binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein N-terminus binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription coactivator activity IDA
Inferred from Direct Assay
more info
PubMed 
transcription coactivator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription corepressor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Cajal body IDA
Inferred from Direct Assay
more info
PubMed 
Gemini of coiled bodies IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
protein NPAT
Names
nuclear protein of the ATM locus
nuclear protein of the ataxia telangiectasia mutated locus
nuclear protein, ataxia-telangiectasia locus
nuclear protein, co-activator of histone transcription

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321307.1NP_001308236.1  protein NPAT isoform 1

    Status: VALIDATED

    Source sequence(s)
    AP001925, AP002433
    Conserved Domains (2) summary
    pfam09528
    Location:244857
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    pfam15712
    Location:7591434
    NPAT_C; NPAT C terminus
  2. NM_002519.2NP_002510.2  protein NPAT isoform 2

    See identical proteins and their annotated locations for NP_002510.2

    Status: VALIDATED

    Source sequence(s)
    AP002433, BC050561, BC094769, DA338219, X97186
    Consensus CDS
    CCDS41710.1
    UniProtKB/Swiss-Prot
    Q14207
    Related
    ENSP00000278612.8, OTTHUMP00000232766, ENST00000278612.8, OTTHUMT00000389506
    Conserved Domains (2) summary
    pfam09528
    Location:244857
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    pfam15712
    Location:7591427
    NPAT_C; NPAT C terminus

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p12 Primary Assembly

    Range
    108155280..108222638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542854.2XP_011541156.1  protein NPAT isoform X1

    Conserved Domains (2) summary
    pfam09528
    Location:244857
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    pfam15712
    Location:7591436
    NPAT_C; NPAT C terminus
  2. XM_017017803.1XP_016873292.1  protein NPAT isoform X2

  3. XM_017017802.1XP_016873291.1  protein NPAT isoform X2

Support Center