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SETD1B SET domain containing 1B, histone lysine methyltransferase [ Canis lupus familiaris (dog) ]

Gene ID: 486257, updated on 25-Jul-2026
Official Symbol
SETD1Bprovided by VGNC
Official Full Name
SET domain containing 1B, histone lysine methyltransferaseprovided by VGNC
Primary source
VGNC:VGNC:46053
See related
Ensembl:ENSCAFG00845023777 RGD:12404478
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See SETD1B in Genome Data Viewer
Location:
chromosome: 26
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (7695608..7719344, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (7603517..7627252, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (7673750..7697486, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (7627485..7651215, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (7717845..7741200, complement)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene proteasome 26S subunit, non-ATPase 9 Neighboring gene uncharacterized LOC102156930 Neighboring gene 4-hydroxyphenylpyruvate dioxygenase Neighboring gene uncharacterized LOC111092641 Neighboring gene uncharacterized LOC119866146 Neighboring gene ras homolog family member F, filopodia associated

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K4 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Set1C/COMPASS complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
histone-lysine N-methyltransferase SETD1B
XP_005636236.2
XP_038292477.1
XP_038292479.1
XP_038314964.1
XP_038367397.1
XP_038367398.1
XP_038430891.1
XP_038430892.1
XP_038495075.1

Length

  • 1972

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    7695608..7719344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436551.1 → XP_038292479.1  histone-lysine N-methyltransferase SETD1B

    UniProtKB/TrEMBL
    A0A8I3PY55
    Related
    ENSCAFP00845032954.1, ENSCAFT00845042017.1
    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)

  2. XM_038436549.1 → XP_038292477.1  histone-lysine N-methyltransferase SETD1B

    UniProtKB/TrEMBL
    A0A8I3PY55
    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    7627485..7651215 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038511470.1 → XP_038367398.1  

    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)

  2. XM_038511469.1 → XP_038367397.1  

    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    7717845..7741200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038639147.1 → XP_038495075.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    7673750..7697486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038574964.1 → XP_038430892.1  histone-lysine N-methyltransferase SETD1B

    UniProtKB/TrEMBL
    A0A8I3PY55
    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)

  2. XM_038574963.1 → XP_038430891.1  histone-lysine N-methyltransferase SETD1B

    UniProtKB/TrEMBL
    A0A8I3PY55
    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7603517..7627252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038459036.1 → XP_038314964.1  histone-lysine N-methyltransferase SETD1B

    UniProtKB/TrEMBL
    A0A8I3PY55
    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)

  2. XM_005636179.4 → XP_005636236.2  histone-lysine N-methyltransferase SETD1B

    UniProtKB/TrEMBL
    A0A8I3PY55
    Conserved Domains (3) summary
    cd19169
    Location:1821 → 1968
    SET_SETD1; SET domain (including post-SET domain) found in SET domain-containing protein 1 (SETD1) and similar proteins
    pfam11764
    Location:1685 → 1827
    N-SET; COMPASS (Complex proteins associated with Set1p) component N
    cd12549
    Location:101 → 193
    RRM_Set1B; RNA recognition motif in vertebrate histone-lysine N-methyltransferase Setd1B (Set1B)
Nucleotide Protein
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