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THAP4 THAP domain containing 4 [ Canis lupus familiaris (dog) ]

Gene ID: 486208, updated on 25-Jul-2026
Official Symbol
THAP4provided by VGNC
Official Full Name
THAP domain containing 4provided by VGNC
Primary source
VGNC:VGNC:59098
See related
Ensembl:ENSCAFG00845023699 RGD:12139130
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Location:
chromosome: 25
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (51654937..51693321, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (51674803..51713677, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (51520478..51559045, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (51504264..51543189, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (51244160..51282359, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene serine/threonine kinase 25 Neighboring gene EZH inhibitory protein-like Neighboring gene BCL2 family apoptosis regulator BOK Neighboring gene autophagy related 4B cysteine peptidase Neighboring gene uncharacterized LOC119865877 Neighboring gene deoxythymidylate kinase

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Homology

Preferred Names
peroxynitrite isomerase THAP4

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    51654937..51693321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436036.1 → XP_038291964.1  peroxynitrite isomerase THAP4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LLB7, A0A8I3PKF7
    Related
    ENSCAFP00845032835.1, ENSCAFT00845041860.1
    Conserved Domains (3) summary
    smart00980
    Location:4 → 85
    THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
    PHA03307
    Location:78 → 340
    PHA03307; transcriptional regulator ICP4; Provisional
    cd07828
    Location:423 → 576
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

  2. XM_038436037.1 → XP_038291965.1  peroxynitrite isomerase THAP4 isoform X2

    Conserved Domains (1) summary
    cd07828
    Location:10 → 163
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    51504264..51543189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510962.1 → XP_038366890.1  

    Conserved Domains (3) summary
    smart00980
    Location:4 → 85
    THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
    PHA03307
    Location:78 → 340
    PHA03307; transcriptional regulator ICP4; Provisional
    cd07828
    Location:423 → 576
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

  2. XM_038510963.1 → XP_038366891.1  

    Conserved Domains (1) summary
    cd07828
    Location:10 → 163
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    51244160..51282359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638689.1 → XP_038494617.1  

    Conserved Domains (3) summary
    smart00980
    Location:4 → 85
    THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
    PHA03307
    Location:78 → 340
    PHA03307; transcriptional regulator ICP4; Provisional
    cd07828
    Location:423 → 576
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

  2. XM_038638690.1 → XP_038494618.1  

    Conserved Domains (1) summary
    cd07828
    Location:10 → 163
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    51520478..51559045 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038574457.1 → XP_038430385.1  peroxynitrite isomerase THAP4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LLB7, A0A8I3PKF7
    Conserved Domains (3) summary
    smart00980
    Location:4 → 85
    THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
    PHA03307
    Location:78 → 340
    PHA03307; transcriptional regulator ICP4; Provisional
    cd07828
    Location:423 → 576
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

  2. XM_038574458.1 → XP_038430386.1  peroxynitrite isomerase THAP4 isoform X2

    Conserved Domains (1) summary
    cd07828
    Location:10 → 163
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    51674803..51713677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458166.1 → XP_038314094.1  peroxynitrite isomerase THAP4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LLB7, A0A8I3PKF7
    Conserved Domains (3) summary
    smart00980
    Location:4 → 85
    THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
    PHA03307
    Location:78 → 340
    PHA03307; transcriptional regulator ICP4; Provisional
    cd07828
    Location:423 → 576
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins

  2. XM_543333.7 → XP_543333.3  peroxynitrite isomerase THAP4 isoform X2

    Conserved Domains (1) summary
    cd07828
    Location:10 → 163
    lipocalin_heme-bd-THAP4-like; heme-binding beta-barrel domain of human THAP4, Arabidopsis thaliana nitrobindin, and similar proteins
Nucleotide Protein
Heading Accession and Version

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