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EFHD1 EF-hand domain family member D1 [ Canis lupus familiaris (dog) ]

Gene ID: 486164, updated on 27-Jun-2026
Official Symbol
EFHD1provided by VGNC
Official Full Name
EF-hand domain family member D1provided by VGNC
Primary source
VGNC:VGNC:59077
See related
Ensembl:ENSCAFG00845026327 RGD:12096420
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See EFHD1 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (44519198..44564677)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (44756345..44801725)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (44445809..44491251)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (44444924..44490319)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (44290617..44336242)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E family member 2 Neighboring gene uncharacterized LOC106557782 Neighboring gene uncharacterized LOC119865966 Neighboring gene GRB10 interacting GYF protein 2 Neighboring gene potassium inwardly rectifying channel subfamily J member 13 Neighboring gene probable ribosome biogenesis protein RLP24

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
EF-hand domain-containing protein D1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    44519198..44564677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435782.1 → XP_038291710.1  EF-hand domain-containing protein D1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PSQ1
    Related
    ENSCAFP00845036461.1, ENSCAFT00845046439.1
    Conserved Domains (1) summary
    cd00051
    Location:100 → 158
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_038435785.1 → XP_038291713.1  EF-hand domain-containing protein D1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LCP9, A0A8C0LF48
    Conserved Domains (1) summary
    cl08302
    Location:2 → 40
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  3. XM_038435783.1 → XP_038291711.1  EF-hand domain-containing protein D1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LF48
    Conserved Domains (1) summary
    cd00051
    Location:24 → 76
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    44444924..44490319
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510711.1 → XP_038366639.1  

    Conserved Domains (1) summary
    cd00051
    Location:98 → 156
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_038510713.1 → XP_038366641.1  

    Conserved Domains (1) summary
    cl08302
    Location:2 → 40
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  3. XM_038510712.1 → XP_038366640.1  

    Conserved Domains (1) summary
    cd00051
    Location:24 → 76
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    44290617..44336242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638486.1 → XP_038494414.1  

    Conserved Domains (1) summary
    cd00051
    Location:98 → 156
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_038638488.1 → XP_038494416.1  

    Conserved Domains (1) summary
    cl08302
    Location:2 → 40
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  3. XM_038638487.1 → XP_038494415.1  

    Conserved Domains (1) summary
    cd00051
    Location:24 → 76
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    44445809..44491251
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038574197.1 → XP_038430125.1  EF-hand domain-containing protein D1 isoform X1

  2. XM_038574199.1 → XP_038430127.1  EF-hand domain-containing protein D1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LCP9, A0A8C0LF48
    Conserved Domains (1) summary
    cl08302
    Location:2 → 40
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  3. XM_038574198.1 → XP_038430126.1  EF-hand domain-containing protein D1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LF48
    Conserved Domains (1) summary
    cd00051
    Location:24 → 76
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    44756345..44801725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458659.1 → XP_038314587.1  EF-hand domain-containing protein D1 isoform X1

    Conserved Domains (1) summary
    cd00051
    Location:98 → 156
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_038458660.1 → XP_038314588.1  EF-hand domain-containing protein D1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LCP9, A0A8C0LF48
    Conserved Domains (1) summary
    cl08302
    Location:2 → 40
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  3. XM_005635855.4 → XP_005635912.4  EF-hand domain-containing protein D1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LF48
    Conserved Domains (1) summary
    cd00051
    Location:24 → 76
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
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