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PDLIM2 PDZ and LIM domain 2 [ Canis lupus familiaris (dog) ]

Gene ID: 486123, updated on 25-Jul-2026
Official Symbol
PDLIM2provided by VGNC
Official Full Name
PDZ and LIM domain 2provided by VGNC
Primary source
VGNC:VGNC:44384
See related
Ensembl:ENSCAFG00845020425 RGD:12237667
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See PDLIM2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (34894441..34907844, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (35274652..35288822, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (34850492..34864707, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (34840878..34855071, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (34694952..34709153, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene cell cycle and apoptosis regulator 2 Neighboring gene chromosome 25 C8orf58 homolog Neighboring gene sorbin and SH3 domain containing 3 Neighboring gene protein phosphatase 3 catalytic subunit gamma

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of filamentous actin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
PDZ and LIM domain protein 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    34894441..34907844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435465.1 → XP_038291393.1  PDZ and LIM domain protein 2

    UniProtKB/TrEMBL
    A0A8I3P9Q2
    Related
    ENSCAFP00845028181.1, ENSCAFT00845036006.1
    Conserved Domains (3) summary
    cd09449
    Location:290 → 342
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:9 → 80
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:210 → 259
    DUF4749; Domain of unknown function (DUF4749)

  2. XM_038435466.1 → XP_038291394.1  PDZ and LIM domain protein 2

    UniProtKB/TrEMBL
    A0A8I3P9Q2
    Conserved Domains (3) summary
    cd09449
    Location:290 → 342
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:9 → 80
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:210 → 259
    DUF4749; Domain of unknown function (DUF4749)

  3. XM_038435467.1 → XP_038291395.1  PDZ and LIM domain protein 2

    UniProtKB/TrEMBL
    A0A8I3P9Q2
    Conserved Domains (3) summary
    cd09449
    Location:290 → 342
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:9 → 80
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:210 → 259
    DUF4749; Domain of unknown function (DUF4749)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    34840878..34855071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510406.1 → XP_038366334.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  2. XM_038510405.1 → XP_038366333.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  3. XM_038510409.1 → XP_038366337.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  4. XM_038510404.1 → XP_038366332.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  5. XM_038510410.1 → XP_038366338.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  6. XM_038510407.1 → XP_038366335.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  7. XM_038510408.1 → XP_038366336.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    34694952..34709153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638173.1 → XP_038494101.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  2. XM_038638172.1 → XP_038494100.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  3. XM_038638176.1 → XP_038494104.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  4. XM_038638171.1 → XP_038494099.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  5. XM_038638174.1 → XP_038494102.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  6. XM_038638175.1 → XP_038494103.1  

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    34850492..34864707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573852.1 → XP_038429780.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  2. XM_038573851.1 → XP_038429779.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  3. XM_038573855.1 → XP_038429783.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  4. XM_038573850.1 → XP_038429778.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  5. XM_038573856.1 → XP_038429784.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  6. XM_038573853.1 → XP_038429781.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  7. XM_038573854.1 → XP_038429782.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    35274652..35288822 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458764.1 → XP_038314692.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  2. XM_038458763.1 → XP_038314691.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  3. XM_038458767.1 → XP_038314695.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  4. XM_014107528.3 → XP_013963003.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  5. XM_038458768.1 → XP_038314696.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  6. XM_022409752.2 → XP_022265460.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)

  7. XM_038458766.1 → XP_038314694.1  PDZ and LIM domain protein 2

    Conserved Domains (3) summary
    cd09449
    Location:292 → 344
    LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
    cd00992
    Location:4 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:212 → 261
    DUF4749; Domain of unknown function (DUF4749)
Nucleotide Protein
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