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NEIL2 nei like DNA glycosylase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 486078, updated on 25-Jul-2026
Official Symbol
NEIL2provided by VGNC
Official Full Name
nei like DNA glycosylase 2provided by VGNC
Primary source
VGNC:VGNC:43727
See related
Ensembl:ENSCAFG00845019176 RGD:12386960
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See NEIL2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (26256928..26271720, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (26759198..26773955, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (26258078..26272833, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (26203051..26224786, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (26106578..26121344, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene cathepsin B Neighboring gene farnesyl-diphosphate farnesyltransferase 1 Neighboring gene GATA binding protein 4 Neighboring gene uncharacterized LOC100685020

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA N-glycosylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
endonuclease 8-like 2
Names
nei endonuclease VIII-like 2
nei like 2
XP_038291167.1
XP_038366113.1
XP_038429576.1
XP_038493877.1
XP_543204.3

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    26256928..26271720 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435239.1 → XP_038291167.1  endonuclease 8-like 2

    UniProtKB/TrEMBL
    A0A8C0KDD8, A0A8I3PG20
    Related
    ENSCAFP00845026478.1, ENSCAFT00845033838.1
    Conserved Domains (2) summary
    PRK01103
    Location:199 → 323
    PRK01103; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase
    cl03119
    Location:1 → 186
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    26203051..26224786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510185.1 → XP_038366113.1  

    Conserved Domains (2) summary
    PRK01103
    Location:199 → 323
    PRK01103; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase
    cl03119
    Location:1 → 186
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    26106578..26121344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038637949.1 → XP_038493877.1  

    Conserved Domains (2) summary
    PRK01103
    Location:199 → 323
    PRK01103; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase
    cl03119
    Location:1 → 186
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    26258078..26272833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573648.1 → XP_038429576.1  endonuclease 8-like 2

    UniProtKB/TrEMBL
    A0A8C0KDD8, A0A8I3PG20
    Conserved Domains (2) summary
    PRK01103
    Location:199 → 323
    PRK01103; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase
    cl03119
    Location:1 → 186
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    26759198..26773955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_543204.7 → XP_543204.3  endonuclease 8-like 2

    UniProtKB/TrEMBL
    A0A8C0KDD8, A0A8C0KH88
    Conserved Domains (2) summary
    cl03119
    Location:1 → 186
    FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases
    cl26942
    Location:199 → 323
    H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain
Nucleotide Protein
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