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MMP24 matrix metallopeptidase 24 [ Canis lupus familiaris (dog) ]

Gene ID: 485849, updated on 1-Mar-2025

Summary

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Official Symbol
MMP24provided by VGNC
Official Full Name
matrix metallopeptidase 24provided by VGNC
Primary source
VGNC:VGNC:43283
See related
Ensembl:ENSCAFG00845018823 RGD:12329618
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See MMP24 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (24907564..24950248)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (23861305..23903980)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (24728551..24771226)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (24194434..24237113)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (24276885..24332128)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865659 Neighboring gene ribosomal protein L21 pseudogene Neighboring gene ER degradation enhancing alpha-mannosidase like protein 2 Neighboring gene protein C receptor Neighboring gene MMP24 opposite strand Neighboring gene family with sequence similarity 83 member C Neighboring gene eukaryotic translation initiation factor 6 Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
matrix metalloproteinase-24

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    24907564..24950248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038433609.1 → XP_038289537.1  matrix metalloproteinase-24 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JY01, A0A8C0QG61, A0A8I3S3N5
    Related
    ENSCAFP00845026055.1, ENSCAFT00845033282.1
    Conserved Domains (4) summary
    cd00094
    Location:362 → 554
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:147 → 312
    Peptidase_M10; Matrixin
    pfam01471
    Location:67 → 119
    PG_binding_1; Putative peptidoglycan binding domain
    pfam11857
    Location:560 → 630
    DUF3377; Domain of unknown function (DUF3377)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    24194434..24237113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038508787.1 → XP_038364715.1  matrix metalloproteinase-24 isoform X1

    Conserved Domains (4) summary
    cd00094
    Location:362 → 554
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:147 → 312
    Peptidase_M10; Matrixin
    pfam01471
    Location:67 → 119
    PG_binding_1; Putative peptidoglycan binding domain
    pfam11857
    Location:560 → 630
    DUF3377; Domain of unknown function (DUF3377)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    24276885..24332128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038635624.1 → XP_038491552.1  matrix metalloproteinase-24 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    24728551..24771226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038572098.1 → XP_038428026.1  matrix metalloproteinase-24 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JY01, A0A8C0QG61, A0A8I3S3N5
    Conserved Domains (4) summary
    cd00094
    Location:362 → 554
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:147 → 312
    Peptidase_M10; Matrixin
    pfam01471
    Location:67 → 119
    PG_binding_1; Putative peptidoglycan binding domain
    pfam11857
    Location:560 → 630
    DUF3377; Domain of unknown function (DUF3377)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23861305..23903980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038457965.1 → XP_038313893.1  matrix metalloproteinase-24 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JY01, A0A8C0QG61, A0A8I3S3N5
    Conserved Domains (4) summary
    cd00094
    Location:362 → 554
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:147 → 312
    Peptidase_M10; Matrixin
    pfam01471
    Location:67 → 119
    PG_binding_1; Putative peptidoglycan binding domain
    pfam11857
    Location:560 → 630
    DUF3377; Domain of unknown function (DUF3377)
Nucleotide Protein
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