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FBXL3 F-box and leucine rich repeat protein 3 [ Canis lupus familiaris (dog) ]

Gene ID: 485499, updated on 25-Jul-2026
Official Symbol
FBXL3provided by VGNC
Official Full Name
F-box and leucine rich repeat protein 3provided by VGNC
Primary source
VGNC:VGNC:54948
See related
Ensembl:ENSCAFG00845026353 RGD:12328980
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See FBXL3 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 22 NC_051826.1 (30891689..30910990, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 22 NC_006604.4 (30440696..30459977, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 22 NC_049243.1 (30666969..30686249, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 22 NC_049282.1 (30559157..30578437, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 22 NC_049763.1 (30597466..30616743, complement)

Chromosome 22 - NC_051826.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091657 Neighboring gene aconitate decarboxylase 1 Neighboring gene CLN5 intracellular trafficking protein Neighboring gene MYC binding protein 2 Neighboring gene clusterin-like Neighboring gene sciellin

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
F-box/LRR-repeat protein 3

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051826.1 Reference ROS_Cfam_1.0

    Range
    30891689..30910990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038431207.1XP_038287135.1  F-box/LRR-repeat protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LH90, A0A8I3PZJ2
    Related
    ENSCAFP00845036470.1, ENSCAFT00845046454.1
    Conserved Domains (2) summary
    sd00034
    Location:174199
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:3677
    F-box-like
  2. XM_038431206.1XP_038287134.1  F-box/LRR-repeat protein 3 isoform X1

    Conserved Domains (2) summary
    sd00034
    Location:184209
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:4687
    F-box-like

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049282.1 Alternate UMICH_Zoey_3.1

    Range
    30559157..30578437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038506588.1XP_038362516.1  

    Conserved Domains (2) summary
    sd00034
    Location:174199
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:3677
    F-box-like
  2. XM_038506587.1XP_038362515.1  

    Conserved Domains (2) summary
    sd00034
    Location:184209
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:4687
    F-box-like

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049763.1 Alternate UNSW_CanFamBas_1.0

    Range
    30597466..30616743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038633941.1XP_038489869.1  

    Conserved Domains (2) summary
    sd00034
    Location:174199
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:3677
    F-box-like
  2. XM_038633940.1XP_038489868.1  

    Conserved Domains (2) summary
    sd00034
    Location:184209
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:4687
    F-box-like

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049243.1 Alternate UU_Cfam_GSD_1.0

    Range
    30666969..30686249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038569786.1XP_038425714.1  F-box/LRR-repeat protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LH90, A0A8I3PZJ2
    Conserved Domains (2) summary
    sd00034
    Location:174199
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:3677
    F-box-like
  2. XM_038569785.1XP_038425713.1  F-box/LRR-repeat protein 3 isoform X1

    Conserved Domains (2) summary
    sd00034
    Location:184209
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:4687
    F-box-like

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006604.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30440696..30459977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_542618.6XP_542618.2  F-box/LRR-repeat protein 3 isoform X2

    See identical proteins and their annotated locations for XP_542618.2

    UniProtKB/TrEMBL
    A0A8C0LH90, A0A8I3PZJ2
    Conserved Domains (2) summary
    sd00034
    Location:174199
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:3677
    F-box-like
  2. XM_022408034.2XP_022263742.1  F-box/LRR-repeat protein 3 isoform X1

    Conserved Domains (2) summary
    sd00034
    Location:184209
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:4687
    F-box-like