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OR52E4B olfactory receptor family 52 subfamily E member 4B [ Canis lupus familiaris (dog) ]

Gene ID: 485309, updated on 22-Jan-2024

Summary

Official Symbol
OR52E4Bprovided by VGNC
Official Full Name
olfactory receptor family 52 subfamily E member 4Bprovided by VGNC
Primary source
VGNC:VGNC:95465
Gene type
protein coding
RefSeq status
INFERRED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
cOR52E4
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

Location:
chromosome: 21
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (29888964..29896567)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (28844066..28845001)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (29573012..29573947)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (29218213..29219148)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (29402487..29403422)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor 52E8-like Neighboring gene olfactory receptor family 52 subfamily E member 8 Neighboring gene olfactory receptor family 52 subfamily E member 4 Neighboring gene olfactory receptor family 52 subfamily E member 7 Neighboring gene olfactory receptor family 52 subfamily E member 5 Neighboring gene olfactory receptor family 56 subfamily A member 4

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
olfactory receptor family 52 subfamily E member 4B
Names
cOR52E4 olfactory receptor family 52 subfamily E-like
olfactory receptor OR9010

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001388720.1NP_001375649.1  olfactory receptor family 52 subfamily E member 4B

    Status: INFERRED

    Source sequence(s)
    JAAUVH010000057
    UniProtKB/TrEMBL
    A0A8P0SVQ1, G3FJG4
    Conserved Domains (1) summary
    cd15952
    Location:27300
    7tmA_OR52E-like; olfactory receptor subfamily 52E and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    29888964..29896567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038429501.1XP_038285429.1  olfactory receptor family 52 subfamily E member 4B isoform X1

    UniProtKB/TrEMBL
    A0A8P0SVQ1, G3FJG4
    Conserved Domains (1) summary
    cd15952
    Location:27300
    7tmA_OR52E-like; olfactory receptor subfamily 52E and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    29218213..29219148
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    29402487..29403422
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    29573012..29573947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    28844066..28845001
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)