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P2RY2 purinergic receptor P2Y2 [ Canis lupus familiaris (dog) ]

Gene ID: 485203, updated on 5-Mar-2024

Summary

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Official Symbol
P2RY2provided by VGNC
Official Full Name
purinergic receptor P2Y2provided by VGNC
Primary source
VGNC:VGNC:44217
See related
Ensembl:ENSCAFG00845008786
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
P2Y2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (25195604..25235719, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (24753351..24793458, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (25105502..25145605, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (24989138..25029222, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (25190157..25231835, complement)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119864981 Neighboring gene pyrimidinergic receptor P2Y6 Neighboring gene uncharacterized LOC111091609 Neighboring gene high mobility group nucleosome-binding domain-containing protein 3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conjunctival expression of the P2Y2 receptor and the effects of 3% diquafosol ophthalmic solution in dogs. Terakado K, et al. Vet J, 2014 Oct. PMID 25178686
  2. P2Y(2) and P2X4 Receptors Mediate Ca(2+) Mobilization in DH82 Canine Macrophage Cells. Sophocleous RA, et al. Int J Mol Sci, 2020 Nov 13. PMID 33202978, Free PMC Article
  3. The apical targeting signal of the P2Y2 receptor is located in its first extracellular loop. Qi AD, et al. J Biol Chem, 2005 Aug 12. PMID 15908695

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. P2Y2 and P2X4 Receptors Mediate Ca(2+) Mobilization in DH82 Canine Macrophage Cells.
    Title: P2Y(2) and P2X4 Receptors Mediate Ca(2+) Mobilization in DH82 Canine Macrophage Cells.
  2. The effect of diquafosol on P2Y2 expression in the conjunctiva and subsequent tear components is reported.
    Title: Conjunctival expression of the P2Y2 receptor and the effects of 3% diquafosol ophthalmic solution in dogs.
  3. the P2Y2 receptor apical targeting signal is located in its first extracellular loop
    Title: The apical targeting signal of the P2Y2 receptor is located in its first extracellular loop.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables A1 adenosine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled UTP receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled purinergic nucleotide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood vessel diameter maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of mucus secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
P2Y purinoceptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    25195604..25235719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038430197.1 → XP_038286125.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038430198.1 → XP_038286126.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038430200.1 → XP_038286128.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Related
    ENSCAFP00845011974.1, ENSCAFT00845015415.1
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038430199.1 → XP_038286127.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038430195.1 → XP_038286123.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  6. XM_038430196.1 → XP_038286124.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_005298708.1 RNA Sequence

  2. XR_005298707.1 RNA Sequence

  3. XR_005298706.1 RNA Sequence

  4. XR_005298703.1 RNA Sequence

  5. XR_005298705.1 RNA Sequence

  6. XR_005298704.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    24989138..25029222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505557.1 → XP_038361485.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038505558.1 → XP_038361486.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038505560.1 → XP_038361488.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038505559.1 → XP_038361487.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038505555.1 → XP_038361483.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  6. XM_038505556.1 → XP_038361484.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_005341913.1 RNA Sequence

  2. XR_005341912.1 RNA Sequence

  3. XR_005341911.1 RNA Sequence

  4. XR_005341908.1 RNA Sequence

  5. XR_005341910.1 RNA Sequence

  6. XR_005341909.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    25190157..25231835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038632905.1 → XP_038488833.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038632906.1 → XP_038488834.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038632908.1 → XP_038488836.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038632907.1 → XP_038488835.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038632904.1 → XP_038488832.1  P2Y purinoceptor 2

    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_005409656.1 RNA Sequence

  2. XR_005409655.1 RNA Sequence

  3. XR_005409654.1 RNA Sequence

  4. XR_005409651.1 RNA Sequence

  5. XR_005409653.1 RNA Sequence

  6. XR_005409652.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    25105502..25145605 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568732.1 → XP_038424660.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038568733.1 → XP_038424661.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038568735.1 → XP_038424663.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038568734.1 → XP_038424662.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038568730.1 → XP_038424658.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  6. XM_038568731.1 → XP_038424659.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_005375681.1 RNA Sequence

  2. XR_005375680.1 RNA Sequence

  3. XR_005375679.1 RNA Sequence

  4. XR_005375676.1 RNA Sequence

  5. XR_005375678.1 RNA Sequence

  6. XR_005375677.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    24753351..24793458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038456249.1 → XP_038312177.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_005633545.4 → XP_005633602.1  P2Y purinoceptor 2

    See identical proteins and their annotated locations for XP_005633602.1

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038456251.1 → XP_038312179.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038456250.1 → XP_038312178.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_014122731.3 → XP_013978206.1  P2Y purinoceptor 2

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  6. XM_005633543.4 → XP_005633600.1  P2Y purinoceptor 2

    See identical proteins and their annotated locations for XP_005633600.1

    UniProtKB/TrEMBL
    A0A8C0JLE1, A0A8C0N8F9, A0A8I3MZ62
    Conserved Domains (1) summary
    cd15373
    Location:34 → 317
    7tmA_P2Y2; P2Y purinoceptor 2, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_005313048.1 RNA Sequence

  2. XR_005313047.1 RNA Sequence

  3. XR_005313046.1 RNA Sequence

  4. XR_005313043.1 RNA Sequence

  5. XR_005313045.1 RNA Sequence

  6. XR_005313044.1 RNA Sequence

Nucleotide Protein
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