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XYL2 D-xylulose reductase (Xylitol dehydrogenase) (XDH) [ Scheffersomyces stipitis CBS 6054 ]

Gene ID: 4852013, updated on 27-Feb-2025
Gene symbol
XYL2
Gene description
D-xylulose reductase (Xylitol dehydrogenase) (XDH)
Locus tag
PICST_86924
Gene type
protein coding
RNA name
D-xylulose reductase (Xylitol dehydrogenase) (XDH)
RefSeq status
PROVISIONAL
Organism
Scheffersomyces stipitis CBS 6054 (strain: CBS 6054)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Scheffersomyces
Orthologs
Candida albicans all
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Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_009068.1 (3415943..3417177)

Chromosome 1 - NC_009068.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ATP synthase delta subunit Neighboring gene mitochondrial 54S ribosomal protein YmL25 Neighboring gene hypothetical protein

Genomic Sequence:
NC_009068.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Thermostabilization of Pichia stipitis xylitol dehydrogenase by mutation of structural zinc-binding loop. Annaluru N, et al. J Biotechnol, 2007 May 10. PMID 17350704
  2. Comparison of SHF and SSF processes from steam-exploded wheat straw for ethanol production by xylose-fermenting and robust glucose-fermenting Saccharomyces cerevisiae strains. Tomás-Pejó E, et al. Biotechnol Bioeng, 2008 Aug 15. PMID 18383076
  3. Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Jeffries TW, et al. Nat Biotechnol, 2007 Mar. PMID 17334359
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Introduced in S.cerevisiae F12, succesfully enable it to metabolize xylose from cereal straw
    Title: Comparison of SHF and SSF processes from steam-exploded wheat straw for ethanol production by xylose-fermenting and robust glucose-fermenting Saccharomyces cerevisiae strains.
  2. A high thermostability of this enzyme was obtained by subsequent site-directed mutagenesis of the structural zinc-binding loop.
    Title: Thermostabilization of Pichia stipitis xylitol dehydrogenase by mutation of structural zinc-binding loop.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-iditol 2-dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in sorbitol catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Names
D-xylulose reductase (Xylitol dehydrogenase) (XDH)
XP_001386982.1
  • Xylitol dehydrogenase (XDH) similar to SOR1 deletion blocks xylitol utilization

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_009068.1 Reference assembly

    Range
    3415943..3417177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001386945.1 → XP_001386982.1  D-xylulose reductase (Xylitol dehydrogenase) (XDH) [Scheffersomyces stipitis CBS 6054]

    See identical proteins and their annotated locations for XP_001386982.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A3GIB4, P22144, Q549G5
    UniProtKB/TrEMBL
    E5G6H4
    Conserved Domains (1) summary
    cd05285
    Location:6 → 361
    sorbitol_DH; Sorbitol dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22144.1

Gene LinkOut

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Molecular Biology Databases
Research Materials