U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 [ Canis lupus familiaris (dog) ]

Gene ID: 485197, updated on 27-Jun-2026
Official Symbol
KCNE3provided by VGNC
Official Full Name
potassium voltage-gated channel subfamily E regulatory subunit 3provided by VGNC
Primary source
VGNC:VGNC:42242
See related
Ensembl:ENSCAFG00845006390 RGD:12173101
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See KCNE3 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (24063194..24076168)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (23625823..23638780)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (23975487..23988456)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (23860571..23873532)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (24057896..24070858)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene DNA polymerase delta 3, accessory subunit Neighboring gene uncharacterized LOC111091531 Neighboring gene lipoyl(octanoyl) transferase 2 Neighboring gene uncharacterized LOC111091533 Neighboring gene phosphoglucomutase 2 like 1 Neighboring gene U6 spliceosomal RNA Neighboring gene prolyl 4-hydroxylase subunit alpha 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables delayed rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane transporter binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane repolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of delayed rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion export across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of heart rate by cardiac conduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ventricular cardiac muscle cell membrane repolarization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ventricular cardiac muscle cell action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
potassium voltage-gated channel subfamily E member 3
Names
potassium voltage-gated channel, Isk-related family, member 3

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    24063194..24076168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038430114.1 → XP_038286042.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  2. XM_038430111.1 → XP_038286039.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  3. XM_038430113.1 → XP_038286041.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  4. XM_038430110.1 → XP_038286038.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Related
    ENSCAFP00845008850.1, ENSCAFT00845011335.1
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  5. XM_038430112.1 → XP_038286040.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    23860571..23873532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505489.1 → XP_038361417.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  2. XM_038505486.1 → XP_038361414.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  3. XM_038505488.1 → XP_038361416.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  4. XM_038505484.1 → XP_038361412.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  5. XM_038505487.1 → XP_038361415.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  6. XM_038505485.1 → XP_038361413.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    24057896..24070858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038632822.1 → XP_038488750.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  2. XM_038632819.1 → XP_038488747.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  3. XM_038632821.1 → XP_038488749.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  4. XM_038632817.1 → XP_038488745.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  5. XM_038632820.1 → XP_038488748.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  6. XM_038632818.1 → XP_038488746.1  

    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    23975487..23988456
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568649.1 → XP_038424577.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  2. XM_038568646.1 → XP_038424574.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  3. XM_038568648.1 → XP_038424576.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  4. XM_038568645.1 → XP_038424573.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  5. XM_038568647.1 → XP_038424575.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23625823..23638780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022407691.2 → XP_022263399.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  2. XM_014122823.3 → XP_013978298.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  3. XM_014122821.3 → XP_013978296.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  4. XM_014122818.3 → XP_013978293.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  5. XM_014122820.3 → XP_013978295.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel

  6. XM_022407690.2 → XP_022263398.1  potassium voltage-gated channel subfamily E member 3

    UniProtKB/TrEMBL
    A0A8C0JKK2, A0A8I3MYQ7
    Conserved Domains (1) summary
    pfam02060
    Location:22 → 92
    ISK_Channel; Slow voltage-gated potassium channel
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous