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HSD11B1L hydroxysteroid 11-beta dehydrogenase 1 like [ Canis lupus familiaris (dog) ]

Gene ID: 485027, updated on 25-Jul-2026
Official Symbol
HSD11B1Lprovided by VGNC
Official Full Name
hydroxysteroid 11-beta dehydrogenase 1 likeprovided by VGNC
Primary source
VGNC:VGNC:41798
See related
Ensembl:ENSCAFG00845013008 RGD:12180537
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See HSD11B1L in Genome Data Viewer
Location:
chromosome: 20
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (54992234..54997427, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (54063122..54068434, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (54732278..54737590, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (54054506..54059817, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (54535013..54540328, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene lon peptidase 1, mitochondrial Neighboring gene ribosomal protein L36 Neighboring gene mitochondrial contact site and cristae organizing system subunit 13 Neighboring gene scaffold attachment factor B Neighboring gene scaffold attachment factor B2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
hydroxysteroid 11-beta-dehydrogenase 1-like protein
XP_005633068.1
XP_005633069.1
XP_038284887.1
XP_038284888.1
XP_038284889.1
XP_038284890.1
XP_038284891.1
XP_038284892.1
XP_038284893.1
XP_038284894.1
XP_038284895.1
XP_038284896.1
XP_038284897.1
XP_038284898.1
XP_038284899.1
XP_038311637.1
XP_038311638.1
XP_038311639.1
XP_038311640.1
XP_038311641.1
XP_038311642.1
XP_038311643.1
XP_038311644.1
XP_038311645.1
XP_038311646.1
XP_038311647.1
XP_038360521.1
XP_038360522.1
XP_038360523.1
XP_038360524.1
XP_038360525.1
XP_038360526.1
XP_038360527.1
XP_038360528.1
XP_038360529.1
XP_038360530.1
XP_038360531.1
XP_038360532.1
XP_038360533.1
XP_038423566.1
XP_038423567.1
XP_038423568.1
XP_038423569.1
XP_038423570.1
XP_038423571.1
XP_038423572.1
XP_038423573.1
XP_038423574.1
XP_038423575.1
XP_038423576.1
XP_038423577.1
XP_038423578.1
XP_038487720.1
XP_038487721.1
XP_038487722.1
XP_038487723.1
XP_038487724.1
XP_038487725.1
XP_038487726.1
XP_038487727.1
XP_038487728.1
XP_038487729.1
XP_038487730.1
XP_038487731.1
XP_038487732.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    54992234..54997427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428964.1 → XP_038284892.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_038428967.1 → XP_038284895.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_038428968.1 → XP_038284896.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

    Conserved Domains (1) summary
    cl21454
    Location:131 → 293
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  4. XM_038428970.1 → XP_038284898.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

  5. XM_038428963.1 → XP_038284891.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  6. XM_038428962.1 → XP_038284890.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  7. XM_038428961.1 → XP_038284889.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  8. XM_038428959.1 → XP_038284887.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  9. XM_038428960.1 → XP_038284888.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  10. XM_038428971.1 → XP_038284899.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

    Conserved Domains (1) summary
    cl21454
    Location:49 → 166
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  11. XM_038428969.1 → XP_038284897.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

    UniProtKB/TrEMBL
    A0A8C0L3A7
    Conserved Domains (1) summary
    cl21454
    Location:40 → 281
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  12. XM_038428965.1 → XP_038284893.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:40 → 236
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  13. XM_038428966.1 → XP_038284894.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Related
    ENSCAFP00845018154.1, ENSCAFT00845023154.1
    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    54054506..54059817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504598.1 → XP_038360526.1  

  2. XM_038504601.1 → XP_038360529.1  

    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_038504602.1 → XP_038360530.1  

  4. XM_038504604.1 → XP_038360532.1  

  5. XM_038504597.1 → XP_038360525.1  

  6. XM_038504596.1 → XP_038360524.1  

  7. XM_038504595.1 → XP_038360523.1  

  8. XM_038504593.1 → XP_038360521.1  

  9. XM_038504594.1 → XP_038360522.1  

  10. XM_038504605.1 → XP_038360533.1  

  11. XM_038504603.1 → XP_038360531.1  

    Conserved Domains (1) summary
    cl21454
    Location:40 → 281
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  12. XM_038504599.1 → XP_038360527.1  

    Conserved Domains (1) summary
    cl21454
    Location:40 → 236
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  13. XM_038504600.1 → XP_038360528.1  

    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    54535013..54540328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631797.1 → XP_038487725.1  

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_038631800.1 → XP_038487728.1  

    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_038631801.1 → XP_038487729.1  

    Conserved Domains (1) summary
    cl21454
    Location:131 → 293
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  4. XM_038631803.1 → XP_038487731.1  

  5. XM_038631796.1 → XP_038487724.1  

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  6. XM_038631795.1 → XP_038487723.1  

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  7. XM_038631794.1 → XP_038487722.1  

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  8. XM_038631792.1 → XP_038487720.1  

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  9. XM_038631793.1 → XP_038487721.1  

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  10. XM_038631804.1 → XP_038487732.1  

    Conserved Domains (1) summary
    cl21454
    Location:49 → 166
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  11. XM_038631802.1 → XP_038487730.1  

    Conserved Domains (1) summary
    cl21454
    Location:40 → 281
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  12. XM_038631798.1 → XP_038487726.1  

    Conserved Domains (1) summary
    cl21454
    Location:40 → 236
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  13. XM_038631799.1 → XP_038487727.1  

    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    54732278..54737590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567643.1 → XP_038423571.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_038567646.1 → XP_038423574.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_038567647.1 → XP_038423575.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

    Conserved Domains (1) summary
    cl21454
    Location:131 → 293
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  4. XM_038567649.1 → XP_038423577.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

  5. XM_038567642.1 → XP_038423570.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  6. XM_038567641.1 → XP_038423569.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  7. XM_038567640.1 → XP_038423568.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  8. XM_038567638.1 → XP_038423566.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  9. XM_038567639.1 → XP_038423567.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  10. XM_038567650.1 → XP_038423578.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

    Conserved Domains (1) summary
    cl21454
    Location:49 → 166
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  11. XM_038567648.1 → XP_038423576.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

    UniProtKB/TrEMBL
    A0A8C0L3A7
    Conserved Domains (1) summary
    cl21454
    Location:40 → 281
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  12. XM_038567644.1 → XP_038423572.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:40 → 236
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  13. XM_038567645.1 → XP_038423573.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    54063122..54068434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038455714.1 → XP_038311642.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_005633012.3 → XP_005633069.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

    See identical proteins and their annotated locations for XP_005633069.1

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_038455716.1 → XP_038311644.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

    Conserved Domains (1) summary
    cl21454
    Location:131 → 293
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  4. XM_038455718.1 → XP_038311646.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

  5. XM_038455713.1 → XP_038311641.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  6. XM_038455712.1 → XP_038311640.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  7. XM_038455711.1 → XP_038311639.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  8. XM_038455709.1 → XP_038311637.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  9. XM_038455710.1 → XP_038311638.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    Conserved Domains (1) summary
    cl21454
    Location:131 → 248
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  10. XM_038455719.1 → XP_038311647.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

    Conserved Domains (1) summary
    cl21454
    Location:49 → 166
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  11. XM_038455717.1 → XP_038311645.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

    UniProtKB/TrEMBL
    A0A8C0L3A7
    Conserved Domains (1) summary
    cl21454
    Location:40 → 281
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  12. XM_038455715.1 → XP_038311643.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:40 → 236
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  13. XM_005633011.4 → XP_005633068.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

    See identical proteins and their annotated locations for XP_005633068.1

    UniProtKB/TrEMBL
    A0A8I3NQG9
    Conserved Domains (1) summary
    cl21454
    Location:27 → 223
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
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