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DNM2 dynamin 2 [ Canis lupus familiaris (dog) ]

Gene ID: 484949, updated on 17-Aug-2024

Summary

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Official Symbol
DNM2provided by VGNC
Official Full Name
dynamin 2provided by VGNC
Primary source
VGNC:VGNC:40033
See related
Ensembl:ENSCAFG00845023306
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See DNM2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (50920493..51009858, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (50271460..50359936, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (50798300..50886770, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (50129310..50218400, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (50556853..50645731, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene chromosome 20 C19orf38 homolog Neighboring gene uncharacterized LOC119864746 Neighboring gene transmembrane p24 trafficking protein 1 Neighboring gene microRNA mir-199-1 Neighboring gene uncharacterized LOC102157235 Neighboring gene queuine tRNA-ribosyltransferase catalytic subunit 1 Neighboring gene interleukin enhancer binding factor 3 Neighboring gene uncharacterized LOC119864747

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamin 2 orchestrates the global actomyosin cytoskeleton for epithelial maintenance and apical constriction. Chua J, et al. Proc Natl Acad Sci U S A, 2009 Dec 8. PMID 19948954, Free PMC Article
  2. RNA interference-mediated knockdown of dynamin 2 reduces endocannabinoid uptake into neuronal dCAD cells. McFarland MJ, et al. Mol Pharmacol, 2008 Jul. PMID 18436710
  3. Dynamin 2 mediates fluid-phase micropinocytosis in epithelial cells. Cao H, et al. J Cell Sci, 2007 Dec 1. PMID 18003703
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GTPase-dependent changes in Dyn2 lead to interactions with different effectors that may differentially modulate endocytosis and/or actomyosin dynamics in polarized cells.
    Title: Dynamin 2 orchestrates the global actomyosin cytoskeleton for epithelial maintenance and apical constriction.
  2. RNA interference-mediated knockdown of DNM2 reduces endocannabinoid uptake into neuronal dCAD cells.
    Title: RNA interference-mediated knockdown of dynamin 2 reduces endocannabinoid uptake into neuronal dCAD cells.
  3. DNM2 mediates fluid-phase micropinocytosis in epithelial cells.
    Title: Dynamin 2 mediates fluid-phase micropinocytosis in epithelial cells.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dynamin-2
XP_003639776.1
XP_003639777.1
XP_003639778.1
XP_005632939.1
XP_005632940.1
XP_005632941.1
XP_005632942.1
XP_005632943.1
XP_005632944.1
XP_005632945.1
XP_005632946.1
XP_022262758.1
XP_022262760.1
XP_038284539.1
XP_038284540.1
XP_038284541.1
XP_038284542.1
XP_038284543.1
XP_038284544.1
XP_038284545.1
XP_038284546.1
XP_038284547.1
XP_038284548.1
XP_038284549.1
XP_038284550.1
XP_038284551.1
XP_038284552.1
XP_038360178.1
XP_038360179.1
XP_038360180.1
XP_038360181.1
XP_038360182.1
XP_038360183.1
XP_038360184.1
XP_038360185.1
XP_038360186.1
XP_038360187.1
XP_038360188.1
XP_038360189.1
XP_038360190.1
XP_038360191.1
XP_038423205.1
XP_038423206.1
XP_038423207.1
XP_038423208.1
XP_038423209.1
XP_038423210.1
XP_038423211.1
XP_038423212.1
XP_038423213.1
XP_038423214.1
XP_038423215.1
XP_038423216.1
XP_038423217.1
XP_038423218.1
XP_038487356.1
XP_038487357.1
XP_038487358.1
XP_038487359.1
XP_038487360.1
XP_038487361.1
XP_038487362.1
XP_038487363.1
XP_038487364.1
XP_038487365.1
XP_038487366.1
XP_038487367.1
XP_038487368.1
XP_038487369.1
XP_867981.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    50920493..51009858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428622.1 → XP_038284550.1  dynamin-2 isoform X12

    UniProtKB/TrEMBL
    A0A8I3PJ94, A0A8P0P8U4
    Related
    ENSCAFP00845032804.1, ENSCAFT00845041820.1
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  2. XM_038428617.1 → XP_038284545.1  dynamin-2 isoform X7

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:757 → 849
    Atrophin-1; Atrophin-1 family

  3. XM_038428623.1 → XP_038284551.1  dynamin-2 isoform X13

    UniProtKB/TrEMBL
    A0A8C0SZZ4
    Related
    ENSCAFP00845032672.1, ENSCAFT00845041663.1
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  4. XM_038428620.1 → XP_038284548.1  dynamin-2 isoform X10

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  5. XM_038428618.1 → XP_038284546.1  dynamin-2 isoform X8

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  6. XM_038428615.1 → XP_038284543.1  dynamin-2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0P214
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  7. XM_038428614.1 → XP_038284542.1  dynamin-2 isoform X4

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:747 → 873
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:524 → 635
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:657 → 745
    GED; Dynamin GTPase effector domain

  8. XM_038428613.1 → XP_038284541.1  dynamin-2 isoform X3

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:752 → 876
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  9. XM_038428611.1 → XP_038284539.1  dynamin-2 isoform X1

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  10. XM_038428621.1 → XP_038284549.1  dynamin-2 isoform X11

    UniProtKB/TrEMBL
    A0A8C0LJA3, A0A8C0SYL7
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  11. XM_038428619.1 → XP_038284547.1  dynamin-2 isoform X9

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  12. XM_038428616.1 → XP_038284544.1  dynamin-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0LKS7, A0A8C0T2P8
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  13. XM_038428612.1 → XP_038284540.1  dynamin-2 isoform X2

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  14. XM_038428624.1 → XP_038284552.1  dynamin-2 isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:577 → 703
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:356 → 465
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:42 → 324
    Dynamin_M; Dynamin central region
    pfam02212
    Location:487 → 575
    GED; Dynamin GTPase effector domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    50129310..50218400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504261.1 → XP_038360189.1  dynamin-2 isoform X12

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  2. XM_038504256.1 → XP_038360184.1  dynamin-2 isoform X7

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:757 → 849
    Atrophin-1; Atrophin-1 family

  3. XM_038504262.1 → XP_038360190.1  dynamin-2 isoform X13

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  4. XM_038504259.1 → XP_038360187.1  dynamin-2 isoform X10

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  5. XM_038504257.1 → XP_038360185.1  dynamin-2 isoform X8

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  6. XM_038504254.1 → XP_038360182.1  dynamin-2 isoform X5

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  7. XM_038504253.1 → XP_038360181.1  dynamin-2 isoform X4

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:747 → 873
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:524 → 635
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:657 → 745
    GED; Dynamin GTPase effector domain

  8. XM_038504252.1 → XP_038360180.1  dynamin-2 isoform X3

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:752 → 876
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  9. XM_038504250.1 → XP_038360178.1  dynamin-2 isoform X1

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  10. XM_038504260.1 → XP_038360188.1  dynamin-2 isoform X11

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  11. XM_038504258.1 → XP_038360186.1  dynamin-2 isoform X9

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  12. XM_038504255.1 → XP_038360183.1  dynamin-2 isoform X6

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  13. XM_038504251.1 → XP_038360179.1  dynamin-2 isoform X2

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  14. XM_038504263.1 → XP_038360191.1  dynamin-2 isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:577 → 703
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:356 → 465
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:42 → 324
    Dynamin_M; Dynamin central region
    pfam02212
    Location:487 → 575
    GED; Dynamin GTPase effector domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    50556853..50645731 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631439.1 → XP_038487367.1  dynamin-2 isoform X12

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  2. XM_038631434.1 → XP_038487362.1  dynamin-2 isoform X7

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:757 → 849
    Atrophin-1; Atrophin-1 family

  3. XM_038631440.1 → XP_038487368.1  dynamin-2 isoform X13

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  4. XM_038631437.1 → XP_038487365.1  dynamin-2 isoform X10

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  5. XM_038631435.1 → XP_038487363.1  dynamin-2 isoform X8

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  6. XM_038631432.1 → XP_038487360.1  dynamin-2 isoform X5

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  7. XM_038631431.1 → XP_038487359.1  dynamin-2 isoform X4

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:747 → 873
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:524 → 635
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:657 → 745
    GED; Dynamin GTPase effector domain

  8. XM_038631430.1 → XP_038487358.1  dynamin-2 isoform X3

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:752 → 876
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  9. XM_038631428.1 → XP_038487356.1  dynamin-2 isoform X1

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  10. XM_038631438.1 → XP_038487366.1  dynamin-2 isoform X11

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  11. XM_038631436.1 → XP_038487364.1  dynamin-2 isoform X9

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  12. XM_038631433.1 → XP_038487361.1  dynamin-2 isoform X6

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  13. XM_038631429.1 → XP_038487357.1  dynamin-2 isoform X2

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  14. XM_038631441.1 → XP_038487369.1  dynamin-2 isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:577 → 703
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:356 → 465
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:42 → 324
    Dynamin_M; Dynamin central region
    pfam02212
    Location:487 → 575
    GED; Dynamin GTPase effector domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    50798300..50886770 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567288.1 → XP_038423216.1  dynamin-2 isoform X12

    UniProtKB/TrEMBL
    A0A8I3PJ94, A0A8P0P8U4
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  2. XM_038567283.1 → XP_038423211.1  dynamin-2 isoform X7

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:757 → 849
    Atrophin-1; Atrophin-1 family

  3. XM_038567289.1 → XP_038423217.1  dynamin-2 isoform X13

    UniProtKB/TrEMBL
    A0A8C0SZZ4
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  4. XM_038567286.1 → XP_038423214.1  dynamin-2 isoform X10

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  5. XM_038567284.1 → XP_038423212.1  dynamin-2 isoform X8

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  6. XM_038567281.1 → XP_038423209.1  dynamin-2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0P214
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  7. XM_038567280.1 → XP_038423208.1  dynamin-2 isoform X4

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:747 → 873
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:524 → 635
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:657 → 745
    GED; Dynamin GTPase effector domain

  8. XM_038567279.1 → XP_038423207.1  dynamin-2 isoform X3

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:752 → 876
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  9. XM_038567277.1 → XP_038423205.1  dynamin-2 isoform X1

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  10. XM_038567287.1 → XP_038423215.1  dynamin-2 isoform X11

    UniProtKB/TrEMBL
    A0A8C0LJA3, A0A8C0SYL7
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  11. XM_038567285.1 → XP_038423213.1  dynamin-2 isoform X9

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  12. XM_038567282.1 → XP_038423210.1  dynamin-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0LKS7, A0A8C0T2P8
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  13. XM_038567278.1 → XP_038423206.1  dynamin-2 isoform X2

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  14. XM_038567290.1 → XP_038423218.1  dynamin-2 isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:577 → 703
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:356 → 465
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:42 → 324
    Dynamin_M; Dynamin central region
    pfam02212
    Location:487 → 575
    GED; Dynamin GTPase effector domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    50271460..50359936 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022407050.1 → XP_022262758.1  dynamin-2 isoform X12

    UniProtKB/TrEMBL
    A0A8I3PJ94, A0A8P0P8U4
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  2. XM_005632886.3 → XP_005632943.1  dynamin-2 isoform X7

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:757 → 849
    Atrophin-1; Atrophin-1 family

  3. XM_005632889.3 → XP_005632946.1  dynamin-2 isoform X13

    UniProtKB/TrEMBL
    A0A8C0SZZ4
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain
    pfam03154
    Location:747 → 839
    Atrophin-1; Atrophin-1 family

  4. XM_003639730.4 → XP_003639778.1  dynamin-2 isoform X10

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  5. XM_005632887.3 → XP_005632944.1  dynamin-2 isoform X8

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  6. XM_862888.6 → XP_867981.3  dynamin-2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0P214
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  7. XM_005632885.3 → XP_005632942.1  dynamin-2 isoform X4

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:747 → 873
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:524 → 635
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:657 → 745
    GED; Dynamin GTPase effector domain

  8. XM_005632884.3 → XP_005632941.1  dynamin-2 isoform X3

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:752 → 876
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  9. XM_005632882.3 → XP_005632939.1  dynamin-2 isoform X1

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  10. XM_003639728.4 → XP_003639776.1  dynamin-2 isoform X11

    UniProtKB/TrEMBL
    A0A8C0LJA3, A0A8C0SYL7
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:737 → 863
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:514 → 625
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:647 → 735
    GED; Dynamin GTPase effector domain

  11. XM_005632888.3 → XP_005632945.1  dynamin-2 isoform X9

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PRK14951
    Location:745 → 865
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  12. XM_003639729.4 → XP_003639777.1  dynamin-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0LKS7, A0A8C0T2P8
    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:741 → 867
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:520 → 629
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 502
    Dynamin_M; Dynamin central region
    pfam02212
    Location:651 → 739
    GED; Dynamin GTPase effector domain

  13. XM_005632883.3 → XP_005632940.1  dynamin-2 isoform X2

    Conserved Domains (5) summary
    smart00053
    Location:6 → 245
    DYNc; Dynamin, GTPase
    PHA03247
    Location:751 → 877
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:530 → 639
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:216 → 498
    Dynamin_M; Dynamin central region
    pfam02212
    Location:661 → 749
    GED; Dynamin GTPase effector domain

  14. XM_022407052.2 → XP_022262760.1  dynamin-2 isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:577 → 703
    PHA03247; large tegument protein UL36; Provisional
    cd01256
    Location:356 → 465
    PH_dynamin; Dynamin pleckstrin homology (PH) domain
    pfam01031
    Location:42 → 324
    Dynamin_M; Dynamin central region
    pfam02212
    Location:487 → 575
    GED; Dynamin GTPase effector domain
Nucleotide Protein
Heading Accession and Version

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