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ECSIT ECSIT signaling integrator [ Canis lupus familiaris (dog) ]

Gene ID: 484938, updated on 27-Jun-2026
Official Symbol
ECSITprovided by VGNC
Official Full Name
ECSIT signaling integratorprovided by VGNC
Primary source
VGNC:VGNC:40188
See related
Ensembl:ENSCAFG00845018379 RGD:12132645
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See ECSIT in Genome Data Viewer
Location:
chromosome: 20
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (50367125..50385358)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (49719951..49738199)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (50246771..50265009)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (49577450..49595682)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (50003598..50021824)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1 Neighboring gene calponin 1 Neighboring gene zinc finger protein 653 Neighboring gene ELAV like RNA binding protein 3 Neighboring gene PRKCSH beta subunit of glucosidase II

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
Names
ECSIT homolog
ECSIT signalling integrator

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    50367125..50385358
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428528.1 → XP_038284456.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  2. XM_038428530.1 → XP_038284458.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  3. XM_038428529.1 → XP_038284457.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  4. XM_038428531.1 → XP_038284459.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Related
    ENSCAFP00845025510.1, ENSCAFT00845032618.1
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    49577450..49595682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504167.1 → XP_038360095.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  2. XM_038504169.1 → XP_038360097.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  3. XM_038504168.1 → XP_038360096.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  4. XM_038504170.1 → XP_038360098.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    50003598..50021824
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631345.1 → XP_038487273.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  2. XM_038631347.1 → XP_038487275.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  3. XM_038631346.1 → XP_038487274.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  4. XM_038631348.1 → XP_038487276.1  

    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    50246771..50265009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567196.1 → XP_038423124.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

  2. XM_038567198.1 → XP_038423126.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

  3. XM_038567197.1 → XP_038423125.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

  4. XM_038567199.1 → XP_038423127.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49719951..49738199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_542054.7 → XP_542054.2  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    See identical proteins and their annotated locations for XP_542054.2

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  2. XM_022407020.2 → XP_022262728.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  3. XM_005632849.3 → XP_005632906.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    See identical proteins and their annotated locations for XP_005632906.1

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein

  4. XM_022407019.1 → XP_022262727.1  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVE2, A0A8I3P655
    Conserved Domains (3) summary
    sd00004
    Location:126 → 171
    PPR; PPR repeat [structural motif]
    pfam06239
    Location:67 → 266
    ECSIT; Evolutionarily conserved signalling intermediate in Toll pathway
    pfam14784
    Location:270 → 393
    ECSIT_C; C-terminal domain of the ECSIT protein
Nucleotide Protein
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