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RNF123 ring finger protein 123 [ Canis lupus familiaris (dog) ]

Gene ID: 484767, updated on 25-Jul-2026
Official Symbol
RNF123provided by VGNC
Official Full Name
ring finger protein 123provided by VGNC
Primary source
VGNC:VGNC:45626
See related
Ensembl:ENSCAFG00845025247 RGD:12062734
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See RNF123 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
38
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (39910535..39939453, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (39473940..39502846, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (39960807..39989722, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (39277607..39306522, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (39680977..39709891, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene inka box actin regulator 1 Neighboring gene cadherin related family member 4 Neighboring gene inositol hexakisphosphate kinase 1 Neighboring gene aminoacyl tRNA synthase complex-interacting multifunctional protein 2-like Neighboring gene GDP-mannose pyrophosphorylase B Neighboring gene adhesion molecule with Ig like domain 3 Neighboring gene macrophage stimulating 1 Neighboring gene acylaminoacyl-peptide hydrolase

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein ligase RNF123
XP_005632592.1
XP_013977334.1
XP_022262434.1
XP_022262435.1
XP_022262436.1
XP_022262437.1
XP_038283657.1
XP_038283658.1
XP_038283659.1
XP_038283661.1
XP_038283662.1
XP_038283663.1
XP_038359343.1
XP_038359344.1
XP_038359345.1
XP_038359346.1
XP_038359347.1
XP_038359348.1
XP_038422345.1
XP_038422346.1
XP_038422347.1
XP_038422348.1
XP_038422349.1
XP_038422350.1
XP_038486494.1
XP_038486495.1
XP_038486496.1
XP_038486497.1
XP_038486498.1
XP_038486499.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    39910535..39939453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427730.1 → XP_038283658.1  E3 ubiquitin-protein ligase RNF123 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  2. XM_038427731.1 → XP_038283659.1  E3 ubiquitin-protein ligase RNF123 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  3. XM_038427734.1 → XP_038283662.1  E3 ubiquitin-protein ligase RNF123 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1256 → 1296
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

  4. XM_038427733.1 → XP_038283661.1  E3 ubiquitin-protein ligase RNF123 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  5. XM_038427729.1 → XP_038283657.1  E3 ubiquitin-protein ligase RNF123 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  6. XM_038427735.1 → XP_038283663.1  E3 ubiquitin-protein ligase RNF123 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L9I4, A0A8I3PU69
    Related
    ENSCAFP00845035034.1, ENSCAFT00845044713.1
    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1252 → 1292
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    39277607..39306522 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503416.1 → XP_038359344.1  

    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  2. XM_038503417.1 → XP_038359345.1  

    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  3. XM_038503419.1 → XP_038359347.1  

    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1256 → 1296
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

  4. XM_038503418.1 → XP_038359346.1  

    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  5. XM_038503415.1 → XP_038359343.1  

    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  6. XM_038503420.1 → XP_038359348.1  

    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1252 → 1292
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    39680977..39709891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630567.1 → XP_038486495.1  

  2. XM_038630568.1 → XP_038486496.1  

  3. XM_038630570.1 → XP_038486498.1  

  4. XM_038630569.1 → XP_038486497.1  

  5. XM_038630566.1 → XP_038486494.1  

  6. XM_038630571.1 → XP_038486499.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    39960807..39989722 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566418.1 → XP_038422346.1  E3 ubiquitin-protein ligase RNF123 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  2. XM_038566419.1 → XP_038422347.1  E3 ubiquitin-protein ligase RNF123 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  3. XM_038566421.1 → XP_038422349.1  E3 ubiquitin-protein ligase RNF123 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1256 → 1296
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

  4. XM_038566420.1 → XP_038422348.1  E3 ubiquitin-protein ligase RNF123 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  5. XM_038566417.1 → XP_038422345.1  E3 ubiquitin-protein ligase RNF123 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  6. XM_038566422.1 → XP_038422350.1  E3 ubiquitin-protein ligase RNF123 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L9I4, A0A8I3PU69
    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1252 → 1292
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39473940..39502846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022406727.2 → XP_022262435.1  E3 ubiquitin-protein ligase RNF123 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  2. XM_022406728.2 → XP_022262436.1  E3 ubiquitin-protein ligase RNF123 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  3. XM_014121859.3 → XP_013977334.1  E3 ubiquitin-protein ligase RNF123 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1256 → 1296
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

  4. XM_022406729.2 → XP_022262437.1  E3 ubiquitin-protein ligase RNF123 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  5. XM_022406726.2 → XP_022262434.1  E3 ubiquitin-protein ligase RNF123 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (1) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123

  6. XM_005632535.4 → XP_005632592.1  E3 ubiquitin-protein ligase RNF123 isoform X5

    See identical proteins and their annotated locations for XP_005632592.1

    UniProtKB/TrEMBL
    A0A8C0L9I4
    Conserved Domains (2) summary
    cd12882
    Location:123 → 250
    SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
    cd16541
    Location:1252 → 1292
    RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins
Nucleotide Protein
Heading Accession and Version

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