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HYAL2 hyaluronidase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 484760, updated on 27-Jun-2026
Official Symbol
HYAL2provided by VGNC
Official Full Name
hyaluronidase 2provided by VGNC
Primary source
VGNC:VGNC:41843
See related
Ensembl:ENSCAFG00845021903 RGD:12230726
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See HYAL2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (39385361..39390488)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (38950366..38955492)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (39436765..39441893)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (38753188..38758313)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (39156748..39161868)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 1 Neighboring gene tumor suppressor 2, mitochondrial calcium regulator Neighboring gene uncharacterized LOC111091327 Neighboring gene hyaluronidase 1 Neighboring gene hyaluronidase 3 Neighboring gene N-alpha-acetyltransferase 80, NatH catalytic subunit

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hyaluronoglucuronidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyalurononglucosaminidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hyaluronan catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
hyaluronidase-2
Names
hyaluronoglucosaminidase 2
XP_005632567.1
XP_005632568.1
XP_005632570.1
XP_038283614.1
XP_038283616.1
XP_038283617.1
XP_038283618.1
XP_038283619.1
XP_038311151.1
XP_038359301.1
XP_038359302.1
XP_038359303.1
XP_038359304.1
XP_038359305.1
XP_038422302.1
XP_038422303.1
XP_038422304.1
XP_038422305.1
XP_038422306.1
XP_038486452.1
XP_038486453.1
XP_038486454.1
XP_038486455.1
XP_038486456.1
XP_541876.2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    39385361..39390488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427690.1 → XP_038283618.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  2. XM_038427686.1 → XP_038283614.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Related
    ENSCAFP00845030372.1, ENSCAFT00845038787.1
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  3. XM_038427688.1 → XP_038283616.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  4. XM_038427691.1 → XP_038283619.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  5. XM_038427689.1 → XP_038283617.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    38753188..38758313
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503376.1 → XP_038359304.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  2. XM_038503373.1 → XP_038359301.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  3. XM_038503374.1 → XP_038359302.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  4. XM_038503377.1 → XP_038359305.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  5. XM_038503375.1 → XP_038359303.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    39156748..39161868
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630527.1 → XP_038486455.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  2. XM_038630524.1 → XP_038486452.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  3. XM_038630525.1 → XP_038486453.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  4. XM_038630528.1 → XP_038486456.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  5. XM_038630526.1 → XP_038486454.1  

    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    39436765..39441893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566377.1 → XP_038422305.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  2. XM_038566374.1 → XP_038422302.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  3. XM_038566375.1 → XP_038422303.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  4. XM_038566378.1 → XP_038422306.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  5. XM_038566376.1 → XP_038422304.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    38950366..38955492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005632513.4 → XP_005632570.1  hyaluronidase-2

    See identical proteins and their annotated locations for XP_005632570.1

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  2. XM_541876.6 → XP_541876.2  hyaluronidase-2

    See identical proteins and their annotated locations for XP_541876.2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  3. XM_005632510.4 → XP_005632567.1  hyaluronidase-2

    See identical proteins and their annotated locations for XP_005632567.1

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  4. XM_038455223.1 → XP_038311151.1  hyaluronidase-2

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase

  5. XM_005632511.3 → XP_005632568.1  hyaluronidase-2

    See identical proteins and their annotated locations for XP_005632568.1

    UniProtKB/TrEMBL
    A0A8C0R5Q5, A0A8I3P9L7
    Conserved Domains (1) summary
    pfam01630
    Location:28 → 357
    Glyco_hydro_56; Hyaluronidase
Nucleotide Protein
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