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DMPK DM1 protein kinase [ Canis lupus familiaris (dog) ]

Gene ID: 484436, updated on 27-Jun-2026
Official Symbol
DMPKprovided by VGNC
Official Full Name
DM1 protein kinaseprovided by VGNC
Primary source
VGNC:VGNC:40001
See related
Ensembl:ENSCAFG00845004793 RGD:12413717
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See DMPK in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (110357335..110368093)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (109309270..109320016)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (110536417..110547165)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (110032956..110043712)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (109667626..109678376)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene symplekin scaffold protein Neighboring gene radial spoke head 6 homolog A Neighboring gene DM1 locus, WD repeat containing Neighboring gene uncharacterized LOC111097810 Neighboring gene meiosis initiator Neighboring gene SIX homeobox 5 Neighboring gene F-box protein 46

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
myotonin-protein kinase
Names
dystrophia myotonica protein kinase
XP_005616487.1
XP_005616488.1
XP_005616493.1
XP_013975070.1
XP_013975077.1
XP_038280498.1
XP_038323750.1
XP_038323751.1
XP_038323752.1
XP_038323753.1
XP_038323754.1
XP_038323755.1
XP_038384472.1
XP_038384473.1
XP_038384474.1
XP_038384475.1
XP_038384476.1
XP_038384478.1
XP_038448750.1
XP_038448751.1
XP_038448752.1
XP_038448753.1
XP_038448754.1
XP_038448755.1
XP_038512552.1
XP_038512553.1
XP_038512554.1
XP_038512555.1
XP_038512556.1
XP_038512557.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    110357335..110368093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038656624.1 → XP_038512552.1  myotonin-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3MUJ0
    Conserved Domains (2) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

  2. XM_038656629.1 → XP_038512557.1  myotonin-protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8C0JR83
    Conserved Domains (3) summary
    pfam08826
    Location:484 → 543
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 401
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
    NF033777
    Location:484 → 628
    M_group_A_cterm; M protein C-terminal domain

  3. XM_038656627.1 → XP_038512555.1  myotonin-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8I3MUJ0
    Related
    ENSCAFP00845006782.1, ENSCAFT00845008597.1
    Conserved Domains (2) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

  4. XM_038656625.1 → XP_038512553.1  myotonin-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0JR83
    Conserved Domains (3) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
    NF033777
    Location:489 → 633
    M_group_A_cterm; M protein C-terminal domain

  5. XM_038656626.1 → XP_038512554.1  myotonin-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3MRG0, A0A8I3MUJ0
    Related
    ENSCAFP00845006778.1, ENSCAFT00845008593.1
    Conserved Domains (2) summary
    pfam08826
    Location:484 → 543
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 401
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

  6. XM_038656628.1 → XP_038512556.1  myotonin-protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8C0JR83
    Conserved Domains (2) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    110032956..110043712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467822.1 → XP_038323750.1  

  2. XM_038467827.1 → XP_038323755.1  

  3. XM_038467825.1 → XP_038323753.1  

    Conserved Domains (2) summary
    pfam08826
    Location:488 → 547
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

  4. XM_038467823.1 → XP_038323751.1  

  5. XM_038467824.1 → XP_038323752.1  

  6. XM_038467826.1 → XP_038323754.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    109667626..109678376
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592822.1 → XP_038448750.1  

  2. XM_038592827.1 → XP_038448755.1  

  3. XM_038592825.1 → XP_038448753.1  

  4. XM_038592823.1 → XP_038448751.1  

  5. XM_038592824.1 → XP_038448752.1  

  6. XM_038592826.1 → XP_038448754.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    110536417..110547165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038528544.1 → XP_038384472.1  myotonin-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0JPU8

  2. XM_038528550.1 → XP_038384478.1  myotonin-protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8C0JR83

  3. XM_038528547.1 → XP_038384475.1  myotonin-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8I3MUJ0

  4. XM_038528545.1 → XP_038384473.1  myotonin-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0JR83

  5. XM_038528546.1 → XP_038384474.1  myotonin-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3MUJ0

  6. XM_038528548.1 → XP_038384476.1  myotonin-protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8C0JR83

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    109309270..109320016
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005616430.3 → XP_005616487.1  myotonin-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3MUJ0
    Conserved Domains (2) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

  2. XM_014119602.3 → XP_013975077.1  myotonin-protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8C0JR83
    Conserved Domains (3) summary
    pfam08826
    Location:484 → 543
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 401
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
    NF033777
    Location:484 → 628
    M_group_A_cterm; M protein C-terminal domain

  3. XM_038424570.1 → XP_038280498.1  myotonin-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8I3MUJ0
    Conserved Domains (2) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

  4. XM_005616431.4 → XP_005616488.1  myotonin-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0JR83
    Conserved Domains (3) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
    NF033777
    Location:489 → 633
    M_group_A_cterm; M protein C-terminal domain

  5. XM_014119595.3 → XP_013975070.1  myotonin-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3MRG0, A0A8I3MUJ0
    Conserved Domains (2) summary
    pfam08826
    Location:484 → 543
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 401
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

  6. XM_005616436.4 → XP_005616493.1  myotonin-protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8C0JR83
    Conserved Domains (2) summary
    pfam08826
    Location:489 → 548
    DMPK_coil; DMPK coiled coil domain like
    cd05597
    Location:69 → 406
    STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
Nucleotide Protein
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