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PTCH1 patched 1 [ Canis lupus familiaris (dog) ]

Gene ID: 484137, updated on 27-Jun-2026
Official Symbol
PTCH1provided by VGNC
Official Full Name
patched 1provided by VGNC
Primary source
VGNC:VGNC:49951
See related
Ensembl:ENSCAFG00845003905 RGD:12174113
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See PTCH1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
31
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (71542960..71613625)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (72001309..72071860)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (71824991..71895587)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (71355076..71425574)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (71118402..71189186)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090717 Neighboring gene uncharacterized LOC119866365 Neighboring gene uncharacterized LOC119870810 Neighboring gene uncharacterized LOC111096354 Neighboring gene uncharacterized LOC102151730 Neighboring gene metal transporter CNNM3-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hedgehog family protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hedgehog receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables smoothened binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
protein patched homolog 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    71542960..71613625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038654956.1 → XP_038510884.1  protein patched homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MR15, A0A8I3N7F5
    Related
    ENSCAFP00845005710.1, ENSCAFT00845007174.1
    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  2. XM_038654955.1 → XP_038510883.1  protein patched homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LH29, A0A8C0LJQ1, A0A8I3MSJ2
    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  3. XM_038654953.1 → XP_038510881.1  protein patched homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LH29, A0A8C0LJQ1, A0A8I3MSJ2
    Related
    ENSCAFP00845005765.1, ENSCAFT00845007249.1
    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  4. XM_038654959.1 → XP_038510887.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Related
    ENSCAFP00845005801.1, ENSCAFT00845007306.1
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  5. XM_038654957.1 → XP_038510885.1  protein patched homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MR15, A0A8I3N7F5
    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  6. XM_038654961.1 → XP_038510889.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  7. XM_038654963.1 → XP_038510891.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  8. XM_038654962.1 → XP_038510890.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  9. XM_038654960.1 → XP_038510888.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  10. XM_038654958.1 → XP_038510886.1  protein patched homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1159 → 1278
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:25 → 1100
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    71355076..71425574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038466169.1 → XP_038322097.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  2. XM_038466168.1 → XP_038322096.1  

    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  3. XM_038466167.1 → XP_038322095.1  

    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  4. XM_038466172.1 → XP_038322100.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  5. XM_038466170.1 → XP_038322098.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  6. XM_038466174.1 → XP_038322102.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  7. XM_038466176.1 → XP_038322104.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  8. XM_038466175.1 → XP_038322103.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  9. XM_038466173.1 → XP_038322101.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  10. XM_038466171.1 → XP_038322099.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1159 → 1278
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:25 → 1100
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    71118402..71189186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038591157.1 → XP_038447085.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  2. XM_038591156.1 → XP_038447084.1  

    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  3. XM_038591155.1 → XP_038447083.1  

    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  4. XM_038591160.1 → XP_038447088.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  5. XM_038591158.1 → XP_038447086.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  6. XM_038591162.1 → XP_038447090.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  7. XM_038591164.1 → XP_038447092.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  8. XM_038591163.1 → XP_038447091.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  9. XM_038591161.1 → XP_038447089.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  10. XM_038591159.1 → XP_038447087.1  

    Conserved Domains (2) summary
    PHA03247
    Location:1159 → 1278
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:25 → 1100
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    71824991..71895587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038526858.1 → XP_038382786.1  protein patched homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MR15, A0A8I3N7F5
    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  2. XM_038526857.1 → XP_038382785.1  protein patched homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LH29, A0A8C0LJQ1, A0A8I3MSJ2
    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  3. XM_038526856.1 → XP_038382784.1  protein patched homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LH29, A0A8C0LJQ1, A0A8I3MSJ2
    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  4. XM_038526861.1 → XP_038382789.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  5. XM_038526859.1 → XP_038382787.1  protein patched homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MR15, A0A8I3N7F5
    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  6. XM_038526863.1 → XP_038382791.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  7. XM_038526865.1 → XP_038382793.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  8. XM_038526864.1 → XP_038382792.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  9. XM_038526862.1 → XP_038382790.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  10. XM_038526860.1 → XP_038382788.1  protein patched homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1159 → 1278
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:25 → 1100
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    72001309..72071860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038562996.1 → XP_038418924.1  protein patched homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MR15, A0A8I3N7F5
    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  2. XM_038562947.1 → XP_038418875.1  protein patched homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LH29, A0A8C0LJQ1, A0A8I3MSJ2
    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  3. XM_003638871.4 → XP_003638919.2  protein patched homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LH29, A0A8C0LJQ1, A0A8I3MSJ2
    Conserved Domains (1) summary
    TIGR00918
    Location:40 → 1204
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  4. XM_038563188.1 → XP_038419116.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  5. XM_038563047.1 → XP_038418975.1  protein patched homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MR15, A0A8I3N7F5
    Conserved Domains (2) summary
    PHA03247
    Location:1199 → 1318
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:2 → 1140
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  6. XM_038563350.1 → XP_038419278.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  7. XM_038563500.1 → XP_038419428.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  8. XM_038563433.1 → XP_038419361.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  9. XM_038563267.1 → XP_038419195.1  protein patched homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK09, A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1114 → 1233
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:1 → 1055
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  10. XM_038563108.1 → XP_038419036.1  protein patched homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3MR15
    Conserved Domains (2) summary
    PHA03247
    Location:1159 → 1278
    PHA03247; large tegument protein UL36; Provisional
    TIGR00918
    Location:25 → 1100
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family
Nucleotide Protein
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