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RNF213 ring finger protein 213 [ Canis lupus familiaris (dog) ]

Gene ID: 483355, updated on 25-Jul-2026
Official Symbol
RNF213provided by VGNC
Official Full Name
ring finger protein 213provided by VGNC
Primary source
VGNC:VGNC:45657
See related
Ensembl:ENSCAFG00845012863 RGD:12243107
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See RNF213 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
68
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (2048400..2146573, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (2056478..2154125, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (2278468..2376800, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (2071964..2170024, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (2197505..2295458, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene neuronal pentraxin 1 Neighboring gene endonuclease V Neighboring gene uncharacterized LOC111097271 Neighboring gene solute carrier family 26 member 11 Neighboring gene N-sulfoglucosamine sulfohydrolase

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein ligase RNF213
XP_038340642.1
XP_038340643.1
XP_038340644.1
XP_038340645.1
XP_038402290.1
XP_038402291.1
XP_038402292.1
XP_038402293.1
XP_038466297.1
XP_038466298.1
XP_038466299.1
XP_038466300.1
XP_038479586.1
XP_038479597.1
XP_038479607.1
XP_038479618.1
XP_038531413.1
XP_038531414.1
XP_038531415.1
XP_038531416.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    2048400..2146573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675487.1 → XP_038531415.1  E3 ubiquitin-protein ligase RNF213 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NEI5
    Conserved Domains (4) summary
    smart00382
    Location:2391 → 2513
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3987 → 4025
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3987 → 4026
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_038675486.1 → XP_038531414.1  E3 ubiquitin-protein ligase RNF213 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NEI5
    Conserved Domains (4) summary
    smart00382
    Location:2390 → 2512
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3986 → 4024
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3986 → 4025
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_038675485.1 → XP_038531413.1  E3 ubiquitin-protein ligase RNF213 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NEI5, A0A8I3RZP8
    Related
    ENSCAFP00845017971.1, ENSCAFT00845022925.1
    Conserved Domains (4) summary
    smart00382
    Location:2391 → 2513
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3986 → 4024
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3986 → 4025
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  4. XM_038675488.1 → XP_038531416.1  E3 ubiquitin-protein ligase RNF213 isoform X4

    Conserved Domains (4) summary
    smart00382
    Location:2391 → 2513
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3987 → 4025
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3987 → 4026
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

RNA

  1. XR_005431855.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    2071964..2170024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484716.1 → XP_038340644.1  

  2. XM_038484715.1 → XP_038340643.1  

  3. XM_038484714.1 → XP_038340642.1  

  4. XM_038484717.1 → XP_038340645.1  

RNA

  1. XR_005330373.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    2197505..2295458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610371.1 → XP_038466299.1  

  2. XM_038610370.1 → XP_038466298.1  

  3. XM_038610369.1 → XP_038466297.1  

  4. XM_038610372.1 → XP_038466300.1  

RNA

  1. XR_005398561.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    2278468..2376800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038546364.1 → XP_038402292.1  E3 ubiquitin-protein ligase RNF213 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NEI5

  2. XM_038546363.1 → XP_038402291.1  E3 ubiquitin-protein ligase RNF213 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NEI5

  3. XM_038546362.1 → XP_038402290.1  E3 ubiquitin-protein ligase RNF213 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NEI5

  4. XM_038546365.1 → XP_038402293.1  E3 ubiquitin-protein ligase RNF213 isoform X4

RNA

  1. XR_005364131.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    2056478..2154125 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623679.1 → XP_038479607.1  E3 ubiquitin-protein ligase RNF213 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NEI5
    Conserved Domains (4) summary
    smart00382
    Location:2391 → 2513
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3987 → 4025
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3987 → 4026
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_038623669.1 → XP_038479597.1  E3 ubiquitin-protein ligase RNF213 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NEI5
    Conserved Domains (4) summary
    smart00382
    Location:2390 → 2512
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3986 → 4024
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3986 → 4025
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_038623658.1 → XP_038479586.1  E3 ubiquitin-protein ligase RNF213 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NEI5
    Conserved Domains (4) summary
    smart00382
    Location:2391 → 2513
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3986 → 4024
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3986 → 4025
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  4. XM_038623690.1 → XP_038479618.1  E3 ubiquitin-protein ligase RNF213 isoform X4

    Conserved Domains (4) summary
    smart00382
    Location:2391 → 2513
    AAA; ATPases associated with a variety of cellular activities
    PHA03247
    Location:58 → 356
    PHA03247; large tegument protein UL36; Provisional
    cd00162
    Location:3987 → 4025
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:3987 → 4026
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

RNA

  1. XR_005405425.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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