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GRB2 growth factor receptor bound protein 2 [ Canis lupus familiaris (dog) ]

Gene ID: 483312, updated on 4-Nov-2022

Summary

Official Symbol
GRB2provided by VGNC
Official Full Name
growth factor receptor bound protein 2provided by VGNC
Primary source
VGNC:VGNC:41472
See related
Ensembl:ENSCAFG00845026938
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See GRB2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (5778347..5852258)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (5787497..5861309)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (5988590..6061075)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (5817381..5891089)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (5927508..6001301)
105 previous assembly CanFam3.1 (GCF_000002285.3) 9 NC_006591.3 (5108128..5182091)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene CASK interacting protein 2 Neighboring gene tRNA splicing endonuclease subunit 54 Neighboring gene transmembrane protein 94 Neighboring gene uncharacterized LOC111097294 Neighboring gene uncharacterized LOC119873225 Neighboring gene solute carrier family 25 member 19 Neighboring gene U4 spliceosomal RNA Neighboring gene MIF4G domain containing Neighboring gene mitochondrial ribosomal protein S7

Genomic regions, transcripts, and products

Pathways from PubChem

General protein information

Preferred Names
growth factor receptor-bound protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    5778347..5852258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675738.1XP_038531666.1  growth factor receptor-bound protein 2

    UniProtKB/TrEMBL
    A0A8C0M7T4, A0A8C0QST7, A0A8I3PT69
    Related
    ENSCAFP00845037253.1, ENSCAFT00845047482.1
    Conserved Domains (3) summary
    cd09941
    Location:56150
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11946
    Location:156
    SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
    cd11949
    Location:160212
    SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    5817381..5891089
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484928.1XP_038340856.1  growth factor receptor-bound protein 2

    Conserved Domains (3) summary
    cd09941
    Location:56150
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11946
    Location:156
    SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
    cd11949
    Location:160212
    SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    5927508..6001301
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610609.1XP_038466537.1  growth factor receptor-bound protein 2

    Conserved Domains (3) summary
    cd09941
    Location:56150
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11946
    Location:156
    SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
    cd11949
    Location:160212
    SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    5988590..6061075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038546617.1XP_038402545.1  growth factor receptor-bound protein 2

    Conserved Domains (3) summary
    cd09941
    Location:56150
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11946
    Location:156
    SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
    cd11949
    Location:160212
    SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    5787497..5861309
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_540431.7XP_540431.2  growth factor receptor-bound protein 2

    See identical proteins and their annotated locations for XP_540431.2

    UniProtKB/TrEMBL
    A0A8C0M7T4, A0A8C0QST7, A0A8I3PT69, J9P9Z6
    Conserved Domains (3) summary
    cd09941
    Location:56150
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11946
    Location:156
    SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
    cd11949
    Location:160212
    SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2