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GRIN2C glutamate ionotropic receptor NMDA type subunit 2C [ Canis lupus familiaris (dog) ]

Gene ID: 483302, updated on 25-Jul-2026
Official Symbol
GRIN2Cprovided by VGNC
Official Full Name
glutamate ionotropic receptor NMDA type subunit 2Cprovided by VGNC
Primary source
VGNC:VGNC:41494
See related
Ensembl:ENSCAFG00845016907 RGD:12131906
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See GRIN2C in Genome Data Viewer
Location:
chromosome: 9
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (6254398..6267415)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (6261897..6274915)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (6462275..6475342)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (6291347..6304344)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (6401937..6414998)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene USH1 protein network component sans Neighboring gene fatty acid desaturase 6 Neighboring gene ferredoxin reductase Neighboring gene solute carrier family 38 member 12 Neighboring gene uncharacterized LOC119873227 Neighboring gene N-acetyltransferase 9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NMDA glutamate receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in excitatory postsynaptic potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-term synaptic potentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NMDA selective glutamate receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
glutamate receptor ionotropic, NMDA 2C
XP_038340886.1

Length

  • 1265

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    6254398..6267415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675767.1 → XP_038531695.1  glutamate receptor ionotropic, NMDA 2C isoform X1

    UniProtKB/TrEMBL
    A0A8I3P9B8
    Conserved Domains (4) summary
    PHA03247
    Location:1031 → 1225
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:444 → 844
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:72 → 428
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:881 → 956
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  2. XM_038675768.1 → XP_038531696.1  glutamate receptor ionotropic, NMDA 2C isoform X2

    UniProtKB/TrEMBL
    A0A8C0LBS6
    Related
    ENSCAFP00845023510.1, ENSCAFT00845029950.1
    Conserved Domains (4) summary
    PHA03247
    Location:987 → 1181
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:400 → 800
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:28 → 384
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:837 → 912
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    6291347..6304344
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484958.1 → XP_038340886.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    6401937..6414998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610639.1 → XP_038466567.1  

    Conserved Domains (4) summary
    PHA03247
    Location:1031 → 1225
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:444 → 844
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:72 → 428
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:881 → 956
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  2. XM_038610640.1 → XP_038466568.1  

    Conserved Domains (4) summary
    PHA03247
    Location:987 → 1181
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:400 → 800
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:28 → 384
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:837 → 912
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    6462275..6475342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038546648.1 → XP_038402576.1  glutamate receptor ionotropic, NMDA 2C isoform X1

    UniProtKB/TrEMBL
    A0A8I3P9B8
    Conserved Domains (4) summary
    PHA03247
    Location:1031 → 1225
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:444 → 844
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:72 → 428
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:881 → 956
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  2. XM_038546649.1 → XP_038402577.1  glutamate receptor ionotropic, NMDA 2C isoform X2

    UniProtKB/TrEMBL
    A0A8C0LBS6
    Conserved Domains (4) summary
    PHA03247
    Location:987 → 1181
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:400 → 800
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:28 → 384
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:837 → 912
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    6261897..6274915
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022422736.2 → XP_022278444.2  glutamate receptor ionotropic, NMDA 2C isoform X1

    UniProtKB/TrEMBL
    A0A8I3P9B8
    Conserved Domains (4) summary
    PHA03247
    Location:1031 → 1225
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:444 → 844
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:72 → 428
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:881 → 956
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  2. XM_038625970.1 → XP_038481898.1  glutamate receptor ionotropic, NMDA 2C isoform X2

    UniProtKB/TrEMBL
    A0A8C0LBS6
    Conserved Domains (4) summary
    PHA03247
    Location:987 → 1181
    PHA03247; large tegument protein UL36; Provisional
    cd13718
    Location:400 → 800
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06378
    Location:28 → 384
    PBP1_iGluR_NMDA_NR2; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    pfam10565
    Location:837 → 912
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
Nucleotide Protein
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