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ttk tramtrack [ Drosophila melanogaster (fruit fly) ]

Gene ID: 48317, updated on 8-Feb-2025

Summary

Official Symbol
ttkprovided by FlyBase
Official Full Name
tramtrackprovided by FlyBase
Primary source
FLYBASE:FBgn0003870
Locus tag
Dmel_CG1856
See related
AllianceGenome:FB:FBgn0003870
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
0037/17; 0250/25; 0438/31; 0702/07; 1049/07; 1119/04; 1184/16; 1209/05; 1209/10; 1260/10; 1281/04; 1325/15; 1372/08; 1396/14; 1418/06; 3540; 5125; 5311; anon-EST:Liang-2.9; CG11558; CG1856; clone 2.9; Dmel\CG1856; E(yan)100D; ftz-f2; FTZ-F2; ftzf2/ttk; l(3)02667; l(3)j2A1; l(3)j7B8; osn; oss; ovs; Tkt69; Tramtrack; tramtrak; Ttk; TTK; ttk/FTZ-F2; ttk69; Ttk69; TTK69; Ttk69k; Ttk88; TTK88; TTKA; ttkp69
Summary
Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; POZ domain binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including compound eye morphogenesis; egg chorion assembly; and open tracheal system development. Located in nucleus and polytene chromosome. Part of transcription repressor complex. Is expressed in several structures, including embryonic/larval midgut primordium; epithelial cell; germ layer; gut section; and pigment cell. [provided by Alliance of Genome Resources, Feb 2025]
Orthologs
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Genomic context

See ttk in Genome Data Viewer
Location:
100D1-100D1; 3-102 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31713867..31735392)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27539589..27561114)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR34046 Neighboring gene uncharacterized protein Neighboring gene Cleavage stimulation factor 50 kD subunit Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in R1/R6 development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in R7 cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in branch fusion, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in branching involved in open tracheal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in chitin-based cuticle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in compound eye cone cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in compound eye corneal lens morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dendrite regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dorsal appendage formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dorsal trunk growth, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in eggshell chorion gene amplification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in enteroendocrine cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epidermal growth factor receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in follicle cell of egg chamber development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in myoblast fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of DNA-templated transcription IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of R7 cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of photoreceptor cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peripheral nervous system development TAS
Traceable Author Statement
more info
PubMed 
involved_in positive regulation of border follicle cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of compound eye cone cell fate specification IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of compound eye cone cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of embryonic cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of tube size, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sevenless signaling pathway IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in tracheal outgrowth, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in polytene chromosome IDA
Inferred from Direct Assay
more info
PubMed 
part_of transcription repressor complex IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
tramtrack
Names
CG1856-PA
CG1856-PB
CG1856-PC
CG1856-PD
CG1856-PE
CG1856-PF
CG1856-PG
CG1856-PH
Tramtrack69
Tramtrack88
Ttk88 repressor
enhancer of yan at 100D
oversensitive
schmal
tramtrack-69
tramtrak
ttk-PA
ttk-PB
ttk-PC
ttk-PD
ttk-PE
ttk-PF
ttk-PG
ttk-PH

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    31713867..31735392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170566.3NP_733445.1  tramtrack, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733445.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q3, P42282, Q0KHY0, Q1LZ43, Q24313, Q9V9V2
    UniProtKB/TrEMBL
    A0A0B4JDG1
    Related
    FBpp0085186
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:612638
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam13894
    Location:646669
    zf-C2H2_4; C2H2-type zinc finger
  2. NM_170568.3NP_733447.1  tramtrack, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733447.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q4, P17789, Q32KE0, Q9V9V1, Q9V9V3
    UniProtKB/TrEMBL
    A0A0B4JD39
    Related
    FBpp0085187
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:510531
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam05605
    Location:507561
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
  3. NM_170565.2NP_733444.1  tramtrack, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733444.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q3, P42282, Q0KHY0, Q1LZ43, Q24313, Q9V9V2
    UniProtKB/TrEMBL
    A0A0B4JDG1
    Related
    FBpp0085188
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:612638
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam13894
    Location:646669
    zf-C2H2_4; C2H2-type zinc finger
  4. NM_080172.4NP_524911.3  tramtrack, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524911.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q4, P17789, Q32KE0, Q9V9V1, Q9V9V3
    UniProtKB/TrEMBL
    A0A0B4JD39
    Related
    FBpp0085189
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:510531
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam05605
    Location:507561
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
  5. NM_170564.3NP_733443.1  tramtrack, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733443.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q3, P42282, Q0KHY0, Q1LZ43, Q24313, Q9V9V2
    UniProtKB/TrEMBL
    A0A0B4JDG1
    Related
    FBpp0085190
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:612638
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam13894
    Location:646669
    zf-C2H2_4; C2H2-type zinc finger
  6. NM_170567.3NP_733446.1  tramtrack, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733446.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q4, P17789, Q32KE0, Q9V9V1, Q9V9V3
    UniProtKB/TrEMBL
    A0A0B4JD39
    Related
    FBpp0085191
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:510531
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam05605
    Location:507561
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
  7. NM_001202400.1NP_001189329.1  tramtrack, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189329.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q3, P42282, Q0KHY0, Q1LZ43, Q24313, Q9V9V2
    UniProtKB/TrEMBL
    A0A0B4JDG1
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:612638
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam13894
    Location:646669
    zf-C2H2_4; C2H2-type zinc finger
  8. NM_001202401.1NP_001189330.1  tramtrack, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189330.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V3Q4, P17789, Q32KE0, Q9V9V1, Q9V9V3
    UniProtKB/TrEMBL
    A0A0B4JD39
    Conserved Domains (4) summary
    smart00225
    Location:34119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00019
    Location:510531
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:23119
    BTB; BTB/POZ domain
    pfam05605
    Location:507561
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding