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DLX6 distal-less homeobox 6 [ Canis lupus familiaris (dog) ]

Gene ID: 482312, updated on 25-Jul-2026
Official Symbol
DLX6provided by VGNC
Official Full Name
distal-less homeobox 6provided by VGNC
Primary source
VGNC:VGNC:54763
See related
Ensembl:ENSCAFG00845021877 RGD:12322400
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See DLX6 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (21882338..21903013)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (21633008..21653659)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (22028123..22048798)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (22029083..22049713)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (21764429..21769915)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866696 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene SEM1 26S proteasome subunit Neighboring gene distal-less homeobox 5 Neighboring gene succinate dehydrogenase complex assembly factor 3 Neighboring gene microRNA mir-8841-2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in embryo development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
homeobox protein DLX-6
XP_038476745.1

Length

  • 291

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    21882338..21903013
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686511.1 → XP_038542439.1  homeobox protein DLX-6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3P985
    Related
    ENSCAFP00845030291.1, ENSCAFT00845038687.1
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

  2. XM_038686512.1 → XP_038542440.1  homeobox protein DLX-6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3P9B5
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

  3. XM_038686513.1 → XP_038542441.1  homeobox protein DLX-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QYY8, A0A8I3P9B5
    Related
    ENSCAFP00845030251.1, ENSCAFT00845038637.1
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

RNA

  1. XR_005437136.1 RNA Sequence

  2. XR_005437135.1 RNA Sequence

  3. XR_005437139.1 RNA Sequence

    Related
    ENSCAFT00845038598.1

  4. XR_005437137.1 RNA Sequence

  5. XR_005437138.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    22029083..22049713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494596.1 → XP_038350524.1  

    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

  2. XM_038494597.1 → XP_038350525.1  

    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

  3. XM_038494598.1 → XP_038350526.1  

    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

RNA

  1. XR_005335638.1 RNA Sequence

  2. XR_005335637.1 RNA Sequence

  3. XR_005335641.1 RNA Sequence

  4. XR_005335639.1 RNA Sequence

  5. XR_005335640.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    21764429..21769915
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620817.1 → XP_038476745.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    22028123..22048798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556878.1 → XP_038412806.1  homeobox protein DLX-6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3P985

  2. XM_038556879.1 → XP_038412807.1  homeobox protein DLX-6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3P9B5
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

  3. XM_038556880.1 → XP_038412808.1  homeobox protein DLX-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QYY8, A0A8I3P9B5
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

RNA

  1. XR_005369410.1 RNA Sequence

  2. XR_005369409.1 RNA Sequence

  3. XR_005369413.1 RNA Sequence

  4. XR_005369411.1 RNA Sequence

  5. XR_005369412.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21633008..21653659
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038440439.1 → XP_038296367.1  homeobox protein DLX-6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3P985
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

  2. XM_038440454.1 → XP_038296382.1  homeobox protein DLX-6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3P9B5
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

  3. XM_038440473.1 → XP_038296401.1  homeobox protein DLX-6 isoform X3

    UniProtKB/TrEMBL
    A0A8I3P9B5
    Conserved Domains (2) summary
    COG5576
    Location:116 → 272
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:167 → 221
    Homeobox; Homeobox domain

RNA

  1. XR_005303683.1 RNA Sequence

  2. XR_005303682.1 RNA Sequence

  3. XR_005303689.1 RNA Sequence

  4. XR_005303685.1 RNA Sequence

  5. XR_005303687.1 RNA Sequence

Nucleotide Protein
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