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ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 [ Canis lupus familiaris (dog) ]

Gene ID: 482192, updated on 1-Mar-2025
Gene symbol
ADAMTS3
Gene description
ADAM metallopeptidase with thrombospondin type 1 motif 3
See related
Ensembl:ENSCAFG00845012236 RGD:12105683
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See ADAMTS3 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
24
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (62087170..62348334, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (60948190..61207761, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (62338060..62599375, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (61697369..61958167, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (61186735..61446690, complement)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene ubiquitin carboxyl-terminal hydrolase 1-like Neighboring gene neuropeptide FF receptor 2 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC102152779 Neighboring gene uncharacterized LOC111098639 Neighboring gene uncharacterized LOC111098638

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. An ADAMTS3 missense variant is associated with Norwich Terrier upper airway syndrome. Marchant TW, et al. PLoS Genet, 2019 May. PMID 31095560, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An ADAMTS3 missense variant is associated with Norwich Terrier upper airway syndrome.
    Title: An ADAMTS3 missense variant is associated with Norwich Terrier upper airway syndrome.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 3
XP_038282561.1
XP_038282567.1
XP_038282572.1
XP_038282579.1
XP_038349934.1
XP_038349935.1
XP_038349936.1
XP_038349937.1
XP_038412225.1
XP_038412226.1
XP_038412227.1
XP_038412228.1
XP_038476164.1
XP_038476165.1
XP_038476166.1
XP_038476167.1
XP_038541793.1
XP_038541794.1
XP_038541795.1
XP_038541796.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    62087170..62348334 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685866.1 → XP_038541794.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 800
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:996 → 1024
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:822 → 877
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038685865.1 → XP_038541793.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X1

    UniProtKB/TrEMBL
    A0A4D6CAB5, A0A8C0LTB7, A0A8C0LTI9, A0A8C0NPK2
    Related
    ENSCAFP00845017121.1, ENSCAFT00845021770.1
    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 827
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:1023 → 1051
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:849 → 904
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038685867.1 → XP_038541795.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038685868.1 → XP_038541796.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    61697369..61958167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494007.1 → XP_038349935.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X2

    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 800
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:996 → 1024
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:822 → 877
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038494006.1 → XP_038349934.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X1

    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 827
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:1023 → 1051
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:849 → 904
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038494008.1 → XP_038349936.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038494009.1 → XP_038349937.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    61186735..61446690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620237.1 → XP_038476165.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X2

    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 800
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:996 → 1024
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:822 → 877
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038620236.1 → XP_038476164.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X1

    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 827
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:1023 → 1051
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:849 → 904
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038620238.1 → XP_038476166.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038620239.1 → XP_038476167.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    62338060..62599375 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556298.1 → XP_038412226.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 800
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:996 → 1024
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:822 → 877
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038556297.1 → XP_038412225.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X1

    UniProtKB/TrEMBL
    A0A4D6CAB5, A0A8C0LTB7, A0A8C0LTI9, A0A8C0NPK2
    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 827
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:1023 → 1051
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:849 → 904
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038556299.1 → XP_038412227.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038556300.1 → XP_038412228.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    60948190..61207761 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426639.1 → XP_038282567.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 800
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:996 → 1024
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:822 → 877
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038426633.1 → XP_038282561.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X1

    UniProtKB/TrEMBL
    A0A4D6CAB5, A0A8C0LTB7, A0A8C0LTI9, A0A8C0NPK2
    Conserved Domains (7) summary
    smart00209
    Location:554 → 606
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:256 → 457
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:713 → 827
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43 → 201
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:1023 → 1051
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:472 → 540
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:849 → 904
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038426644.1 → XP_038282572.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038426651.1 → XP_038282579.1  A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LTI9
    Conserved Domains (7) summary
    smart00209
    Location:384 → 436
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:86 → 287
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:543 → 657
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:1 → 31
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:853 → 881
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:302 → 370
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:679 → 734
    TSP1_ADAMTS; Thrombospondin type 1 domain
Nucleotide Protein
Heading Accession and Version

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