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OPLAH 5-oxoprolinase, ATP-hydrolysing [ Canis lupus familiaris (dog) ]

Gene ID: 482085, updated on 25-Jul-2026
Official Symbol
OPLAHprovided by VGNC
Official Full Name
5-oxoprolinase, ATP-hydrolysingprovided by VGNC
Primary source
VGNC:VGNC:49607
See related
Ensembl:ENSCAFG00845007462 RGD:12383136
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See OPLAH in Genome Data Viewer
Location:
chromosome: 13
Exon count:
27
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (38031277..38041053, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (37518691..37530749, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (38308149..38320210, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (37703380..37715418, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (37831555..37843631, complement)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098587 Neighboring gene spermatogenesis and centriole associated 1 Neighboring gene translation initiation factor IF-2-like Neighboring gene sphingomyelin phosphodiesterase 5 Neighboring gene uncharacterized LOC119864653 Neighboring gene uncharacterized LOC119865005 Neighboring gene exosome component 4

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5-oxoprolinase (ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
5-oxoprolinase
XP_038283058.1
XP_038283063.1
XP_038349412.1
XP_038349413.1
XP_038411715.1
XP_038475635.1
XP_038475636.1
XP_038541238.1
XP_038541239.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    38031277..38041053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685311.1 → XP_038541239.1  5-oxoprolinase isoform X1

    Conserved Domains (1) summary
    PLN02666
    Location:1 → 1268
    PLN02666; 5-oxoprolinase

  2. XM_038685310.1 → XP_038541238.1  5-oxoprolinase isoform X2

    Related
    ENSCAFP00845010240.1, ENSCAFT00845013172.1
    Conserved Domains (1) summary
    PLN02666
    Location:1 → 1258
    PLN02666; 5-oxoprolinase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    37703380..37715418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038493484.1 → XP_038349412.1  

    Conserved Domains (2) summary
    PLN02666
    Location:117 → 1374
    PLN02666; 5-oxoprolinase
    pfam15058
    Location:1 → 66
    Speriolin_N; Speriolin N-terminus

  2. XM_038493485.1 → XP_038349413.1  

    Conserved Domains (1) summary
    PLN02666
    Location:1 → 1268
    PLN02666; 5-oxoprolinase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    37831555..37843631 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038619707.1 → XP_038475635.1  

  2. XM_038619708.1 → XP_038475636.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    38308149..38320210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038555787.1 → XP_038411715.1  5-oxoprolinase isoform X5

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    37518691..37530749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427130.1 → XP_038283058.1  5-oxoprolinase isoform X6

    Conserved Domains (2) summary
    PLN02666
    Location:117 → 1374
    PLN02666; 5-oxoprolinase
    pfam15058
    Location:1 → 66
    Speriolin_N; Speriolin N-terminus

  2. XM_038427135.1 → XP_038283063.1  5-oxoprolinase isoform X1

    Conserved Domains (1) summary
    PLN02666
    Location:1 → 1268
    PLN02666; 5-oxoprolinase
Nucleotide Protein
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