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GABRR2 gamma-aminobutyric acid type A receptor subunit rho2 [ Canis lupus familiaris (dog) ]

Gene ID: 481918, updated on 5-Mar-2024

Summary

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Official Symbol
GABRR2provided by VGNC
Official Full Name
gamma-aminobutyric acid type A receptor subunit rho2provided by VGNC
Primary source
VGNC:VGNC:57240
See related
Ensembl:ENSCAFG00845006659
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (49300885..49346708, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (48298970..48344788, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (48708571..48754457, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (48616699..48663008, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (48515291..48561811, complement)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene peptidase M20 domain containing 2 Neighboring gene gamma-aminobutyric acid type A receptor subunit rho1 Neighboring gene uncharacterized LOC119874298 Neighboring gene uncharacterized LOC111098355 Neighboring gene ubiquitin conjugating enzyme E2 J1 Neighboring gene Ras related GTP binding D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GABA-A receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables extracellular ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of GABA-A receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-aminobutyric acid receptor subunit rho-2
Names
gamma-aminobutyric acid (GABA) receptor, rho 2
gamma-aminobutyric acid type A receptor rho2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    49300885..49346708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038684151.1 → XP_038540079.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MT74
    Related
    ENSCAFP00845009289.1, ENSCAFT00845011907.1
    Conserved Domains (2) summary
    TIGR00860
    Location:86 → 489
    LIC; Cation transporter family protein
    cd19005
    Location:101 → 286
    LGIC_ECD_GABAAR_rho; extracellular domain of gamma-aminobutyric acid receptor subunit rho

  2. XM_038684152.1 → XP_038540080.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:1 → 369
    LIC; Cation transporter family protein
    cd03558
    Location:83 → 97
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 166
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    48616699..48663008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038492426.1 → XP_038348354.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X1

  2. XM_038492427.1 → XP_038348355.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    48515291..48561811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038618592.1 → XP_038474520.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X1

  2. XM_038618593.1 → XP_038474521.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    48708571..48754457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038554722.1 → XP_038410650.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MT74
    Conserved Domains (2) summary
    TIGR00860
    Location:86 → 489
    LIC; Cation transporter family protein
    cd19005
    Location:101 → 286
    LGIC_ECD_GABAAR_rho; extracellular domain of gamma-aminobutyric acid receptor subunit rho

  2. XM_038554723.1 → XP_038410651.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:1 → 369
    LIC; Cation transporter family protein
    cd03558
    Location:83 → 97
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 166
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    48298970..48344788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_539039.6 → XP_539039.2  gamma-aminobutyric acid receptor subunit rho-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N069, A0A8P0N610
    Conserved Domains (3) summary
    TIGR00860
    Location:86 → 489
    LIC; Cation transporter family protein
    pfam02931
    Location:87 → 286
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:293 → 486
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  2. XM_022426349.2 → XP_022282057.1  gamma-aminobutyric acid receptor subunit rho-2 isoform X2

    Conserved Domains (1) summary
    cl27321
    Location:1 → 369
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
Nucleotide Protein
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