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ABCA1 ATP binding cassette subfamily A member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 481651, updated on 17-Aug-2024

Summary

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Official Symbol
ABCA1provided by VGNC
Official Full Name
ATP binding cassette subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:37422
See related
Ensembl:ENSCAFG00845010374
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
51
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (61895159..62023474, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (59222894..59351153, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (61125735..61254053, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (60416579..60544839, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (60430633..60559576, complement)

Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873958 Neighboring gene protein BTG4-like Neighboring gene protein NipSnap homolog 3A Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111098116 Neighboring gene uncharacterized LOC119873959

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HMG-CoA reductase inhibitors (statins) activate expression of PPARalpha/PPARgamma and ABCA1 in cultured gallbladder epithelial cells. Lee J, et al. Dig Dis Sci, 2010 Feb. PMID 19225884

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Simvastatin, pravastatin, and NO-pravastatin increased expression of the proteins PPARalpha, PPARgamma, and ABCA1, and expression of the mRNA of ABCA1 and LXRalpha in GBEC.
    Title: HMG-CoA reductase inhibitors (statins) activate expression of PPARalpha/PPARgamma and ABCA1 in cultured gallbladder epithelial cells.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipid transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-binding cassette sub-family A member 1; phospholipid-transporting ATPase ABCA1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051815.1 Reference ROS_Cfam_1.0

    Range
    61895159..62023474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038682334.1 → XP_038538262.1  phospholipid-transporting ATPase ABCA1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L766
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2238
    rim_protein; retinal-specific rim ABC transporter

  2. XM_038682336.1 → XP_038538264.1  phospholipid-transporting ATPase ABCA1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L766, A0A8C0NNR5, A0A8I3RVS5
    Related
    ENSCAFP00845014286.1, ENSCAFT00845018307.1
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2236
    rim_protein; retinal-specific rim ABC transporter

  3. XM_038682333.1 → XP_038538261.1  phospholipid-transporting ATPase ABCA1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2239
    rim_protein; retinal-specific rim ABC transporter

  4. XM_038682335.1 → XP_038538263.1  phospholipid-transporting ATPase ABCA1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3
    Related
    ENSCAFP00845014454.1, ENSCAFT00845018528.1
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2237
    rim_protein; retinal-specific rim ABC transporter

  5. XM_038682337.1 → XP_038538265.1  phospholipid-transporting ATPase ABCA1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2146
    rim_protein; retinal-specific rim ABC transporter

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049271.1 Alternate UMICH_Zoey_3.1

    Range
    60416579..60544839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038490877.1 → XP_038346805.1  phospholipid-transporting ATPase ABCA1 isoform X2

    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2238
    rim_protein; retinal-specific rim ABC transporter

  2. XM_038490879.1 → XP_038346807.1  phospholipid-transporting ATPase ABCA1 isoform X4

    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2236
    rim_protein; retinal-specific rim ABC transporter

  3. XM_038490876.1 → XP_038346804.1  phospholipid-transporting ATPase ABCA1 isoform X1

    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2239
    rim_protein; retinal-specific rim ABC transporter

  4. XM_038490878.1 → XP_038346806.1  phospholipid-transporting ATPase ABCA1 isoform X3

    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2237
    rim_protein; retinal-specific rim ABC transporter

  5. XM_038490880.1 → XP_038346808.1  phospholipid-transporting ATPase ABCA1 isoform X5

    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2146
    rim_protein; retinal-specific rim ABC transporter

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

    Range
    60430633..60559576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038616882.1 → XP_038472810.1  phospholipid-transporting ATPase ABCA1 isoform X2

  2. XM_038616884.1 → XP_038472812.1  phospholipid-transporting ATPase ABCA1 isoform X4

  3. XM_038616881.1 → XP_038472809.1  phospholipid-transporting ATPase ABCA1 isoform X1

  4. XM_038616883.1 → XP_038472811.1  phospholipid-transporting ATPase ABCA1 isoform X3

  5. XM_038616885.1 → XP_038472813.1  phospholipid-transporting ATPase ABCA1 isoform X5

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

    Range
    61125735..61254053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038553000.1 → XP_038408928.1  phospholipid-transporting ATPase ABCA1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L766

  2. XM_038553002.1 → XP_038408930.1  phospholipid-transporting ATPase ABCA1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L766

  3. XM_038552999.1 → XP_038408927.1  phospholipid-transporting ATPase ABCA1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3

  4. XM_038553001.1 → XP_038408929.1  phospholipid-transporting ATPase ABCA1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3

  5. XM_038553003.1 → XP_038408931.1  phospholipid-transporting ATPase ABCA1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    59222894..59351153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022425669.2 → XP_022281377.1  phospholipid-transporting ATPase ABCA1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L766
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2238
    rim_protein; retinal-specific rim ABC transporter

  2. XM_014117894.3 → XP_013973369.1  phospholipid-transporting ATPase ABCA1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L766, A0A8C0NNR5, A0A8I3RVS5
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2236
    rim_protein; retinal-specific rim ABC transporter

  3. XM_022425668.2 → XP_022281376.1  phospholipid-transporting ATPase ABCA1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2239
    rim_protein; retinal-specific rim ABC transporter

  4. XM_014117893.3 → XP_013973368.1  phospholipid-transporting ATPase ABCA1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2237
    rim_protein; retinal-specific rim ABC transporter

  5. XM_022425670.2 → XP_022281378.1  phospholipid-transporting ATPase ABCA1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NF64, A0A8P0NYQ3
    Conserved Domains (1) summary
    TIGR01257
    Location:6 → 2146
    rim_protein; retinal-specific rim ABC transporter
Nucleotide Protein
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