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WSB1 WD repeat and SOCS box containing 1 [ Canis lupus familiaris (dog) ]

Gene ID: 480619, updated on 27-Jun-2026
Official Symbol
WSB1provided by VGNC
Official Full Name
WD repeat and SOCS box containing 1provided by VGNC
Primary source
VGNC:VGNC:48435
See related
Ensembl:ENSCAFG00845014337 RGD:12213392
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See WSB1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (42686073..42703082)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (41026914..41043875)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (41840239..41857179)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (41469038..41486023)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (41763701..41780612)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102151448 Neighboring gene uncharacterized LOC102151497 Neighboring gene uncharacterized LOC111097438 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene kinase suppressor of ras 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
WD repeat and SOCS box-containing protein 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    42686073..42703082
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038677425.1 → XP_038533353.1  WD repeat and SOCS box-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R0N2, A0A8I3NHU3
    Related
    ENSCAFP00845020255.1, ENSCAFT00845025702.1
    Conserved Domains (3) summary
    cd00200
    Location:135 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:382 → 421
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  2. XM_038677426.1 → XP_038533354.1  WD repeat and SOCS box-containing protein 1 isoform X2

    Conserved Domains (3) summary
    cd00200
    Location:135 → 350
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:344 → 383
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  3. XM_038677427.1 → XP_038533355.1  WD repeat and SOCS box-containing protein 1 isoform X3

    Conserved Domains (3) summary
    cd00200
    Location:135 → 335
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:338 → 377
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:173 → 209
    7WD40; WD40 repeat [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    41469038..41486023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038486371.1 → XP_038342299.1  

    Conserved Domains (3) summary
    cd00200
    Location:135 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:382 → 421
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  2. XM_038486372.1 → XP_038342300.1  

    Conserved Domains (3) summary
    cd00200
    Location:135 → 350
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:344 → 383
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  3. XM_038486373.1 → XP_038342301.1  

    Conserved Domains (3) summary
    cd00200
    Location:135 → 335
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:338 → 377
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:173 → 209
    7WD40; WD40 repeat [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    41763701..41780612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038612170.1 → XP_038468098.1  

    Conserved Domains (3) summary
    cd00200
    Location:135 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:382 → 421
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  2. XM_038612171.1 → XP_038468099.1  

    Conserved Domains (3) summary
    cd00200
    Location:135 → 350
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:344 → 383
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  3. XM_038612172.1 → XP_038468100.1  

    Conserved Domains (3) summary
    cd00200
    Location:135 → 335
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:338 → 377
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:173 → 209
    7WD40; WD40 repeat [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    41840239..41857179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038548208.1 → XP_038404136.1  WD repeat and SOCS box-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R0N2, A0A8I3NHU3
    Conserved Domains (3) summary
    cd00200
    Location:135 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:382 → 421
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  2. XM_038548209.1 → XP_038404137.1  WD repeat and SOCS box-containing protein 1 isoform X2

    Conserved Domains (3) summary
    cd00200
    Location:135 → 350
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:344 → 383
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  3. XM_038548210.1 → XP_038404138.1  WD repeat and SOCS box-containing protein 1 isoform X3

    Conserved Domains (3) summary
    cd00200
    Location:135 → 335
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:338 → 377
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:173 → 209
    7WD40; WD40 repeat [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41026914..41043875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_848852.6 → XP_853945.1  WD repeat and SOCS box-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R0N2, A0A8I3NHU3
    Conserved Domains (3) summary
    cd00200
    Location:135 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:382 → 421
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  2. XM_038610304.1 → XP_038466232.1  WD repeat and SOCS box-containing protein 1 isoform X2

    Conserved Domains (3) summary
    cd00200
    Location:135 → 350
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:344 → 383
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:174 → 212
    7WD40; WD40 repeat [structural motif]

  3. XM_014116769.3 → XP_013972244.1  WD repeat and SOCS box-containing protein 1 isoform X3

    Conserved Domains (3) summary
    cd00200
    Location:135 → 335
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd03746
    Location:338 → 377
    SOCS_WSB1_SWIP1; SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1 ...
    sd00039
    Location:173 → 209
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
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