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BECN1 beclin 1 [ Canis lupus familiaris (dog) ]

Gene ID: 480513, updated on 26-Sep-2018

Summary

Gene symbol
BECN1
Gene description
beclin 1
See related
Ensembl:ENSCAFG00000014638
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs

Genomic context

See BECN1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
13
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 9 NC_006591.3 (20204203..20215081)

Chromosome 9 - NC_006591.3Genomic Context describing neighboring genes Neighboring gene amine oxidase, copper containing 2 Neighboring gene proteasome activator subunit 3 Neighboring gene cyclin N-terminal domain containing 1 Neighboring gene coiled-coil domain containing 56 Neighboring gene WNK lysine deficient protein kinase 4

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006591.3 Chromosome 9 Reference CanFam3.1 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Apelin signaling pathway, organism-specific biosystem (from KEGG)
    Apelin signaling pathway, organism-specific biosystemApelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally described as an orphan G-protein-coupled receptor. Apelin and APJ are widely expressed in various ti...
  • Apoptosis - multiple species, organism-specific biosystem (from KEGG)
    Apoptosis - multiple species, organism-specific biosystemApoptosis is an evolutionarily conserved process used by multicellular organisms to developmentally regulate cell number or to eliminate cells that are potentially detrimental to the organism. The ma...
  • Apoptosis - multiple species, conserved biosystem (from KEGG)
    Apoptosis - multiple species, conserved biosystemApoptosis is an evolutionarily conserved process used by multicellular organisms to developmentally regulate cell number or to eliminate cells that are potentially detrimental to the organism. The ma...
  • Autophagy - animal, organism-specific biosystem (from KEGG)
    Autophagy - animal, organism-specific biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
  • Autophagy - animal, conserved biosystem (from KEGG)
    Autophagy - animal, conserved biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
  • Autophagy - other, organism-specific biosystem (from KEGG)
    Autophagy - other, organism-specific biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
  • Autophagy - other, conserved biosystem (from KEGG)
    Autophagy - other, conserved biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
  • Mitophagy - animal, organism-specific biosystem (from KEGG)
    Mitophagy - animal, organism-specific biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
  • Mitophagy - animal, conserved biosystem (from KEGG)
    Mitophagy - animal, conserved biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...

General gene information

Markers

Homology

General protein information

Preferred Names
Beclin-1; beclin-1
Names
beclin 1, autophagy related

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006591.3 Reference CanFam3.1 Primary Assembly

    Range
    20204203..20215081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_537634.6XP_537634.3  beclin-1 isoform X2

    Related
    ENSCAFP00000021764.3, ENSCAFT00000023434.3
    Conserved Domains (2) summary
    pfam15285
    Location:105127
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
    pfam04111
    Location:133443
    APG6; Autophagy protein Apg6
  2. XM_005624442.3XP_005624499.1  beclin-1 isoform X1

    Conserved Domains (2) summary
    pfam15285
    Location:128150
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
    pfam04111
    Location:156466
    APG6; Autophagy protein Apg6
  3. XM_022422964.1XP_022278672.1  beclin-1 isoform X1

    Conserved Domains (2) summary
    pfam15285
    Location:128150
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
    pfam04111
    Location:156466
    APG6; Autophagy protein Apg6
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