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TTC8 tetratricopeptide repeat domain 8 [ Canis lupus familiaris (dog) ]

Gene ID: 480413, updated on 5-Mar-2024

Summary

Official Symbol
TTC8provided by VGNC
Official Full Name
tetratricopeptide repeat domain 8provided by VGNC
Primary source
VGNC:VGNC:47963
See related
Ensembl:ENSCAFG00845012241
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See TTC8 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (60332658..60386187)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (59641066..59693906)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (60391356..60444177)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (60013742..60066541)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (60063485..60116262)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 14 Neighboring gene 40S ribosomal protein S15a-like Neighboring gene EMAP like 5 Neighboring gene forkhead box N3 Neighboring gene uncharacterized LOC111097135 Neighboring gene uncharacterized LOC102156073

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in non-motile cilium assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of BBSome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in ciliary basal body IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in non-motile cilium IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
tetratricopeptide repeat protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284469.1NP_001271398.1  tetratricopeptide repeat protein 8

    See identical proteins and their annotated locations for NP_001271398.1

    Status: PROVISIONAL

    Source sequence(s)
    JQ941743
    UniProtKB/TrEMBL
    A0A8C0KVK4, A0A8C0PUU0, A0A8P0SWK4, R4ITK9
    Conserved Domains (2) summary
    COG0457
    Location:231488
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:220243
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    60332658..60386187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038672886.1XP_038528814.1  tetratricopeptide repeat protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NKT7, A0A8I3NM60
    Related
    ENSCAFP00845017191.1, ENSCAFT00845021855.1
    Conserved Domains (3) summary
    COG0457
    Location:241498
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:230253
    TPR; TPR repeat [structural motif]
    cd21341
    Location:30179
    TTC8_N; N-terminal domain of tetratricopeptide repeat domain 8
  2. XM_038672889.1XP_038528817.1  tetratricopeptide repeat protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NLA0, A0A8I3NPG7
    Related
    ENSCAFP00845017438.1, ENSCAFT00845022177.1
    Conserved Domains (3) summary
    COG0457
    Location:181438
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:170193
    TPR; TPR repeat [structural motif]
    cd21341
    Location:1119
    TTC8_N; N-terminal domain of tetratricopeptide repeat domain 8
  3. XM_038672888.1XP_038528816.1  tetratricopeptide repeat protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NLA0
    Related
    ENSCAFP00845017373.1, ENSCAFT00845022096.1
    Conserved Domains (3) summary
    COG0457
    Location:194451
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:183206
    TPR; TPR repeat [structural motif]
    cd21341
    Location:2132
    TTC8_N; N-terminal domain of tetratricopeptide repeat domain 8

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    60013742..60066541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    60063485..60116262
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    60391356..60444177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    59641066..59693906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)