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IPO4 importin 4 [ Canis lupus familiaris (dog) ]

Gene ID: 480260, updated on 25-Jul-2026
Official Symbol
IPO4provided by VGNC
Official Full Name
importin 4provided by VGNC
Primary source
VGNC:VGNC:42065
See related
Ensembl:ENSCAFG00845005891 RGD:12094679
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See IPO4 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
30
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (4282317..4291213, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (4093204..4102330, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (4296844..4305741, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (3972710..3981604, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (4034535..4043435, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene interferon regulatory factor 9 Neighboring gene uncharacterized LOC111096970 Neighboring gene REC8 meiotic recombination protein Neighboring gene transmembrane 9 superfamily member 1 Neighboring gene 60S ribosomal protein L37-like Neighboring gene testis specific serine kinase 4

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear import signal receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
importin-4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    4282317..4291213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038673202.1 → XP_038529130.1  importin-4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MZI1
    Related
    ENSCAFP00845008359.1, ENSCAFT00845010721.1
    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

  2. XM_038673203.1 → XP_038529131.1  importin-4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MZI1
    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    3972710..3981604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038482842.1 → XP_038338770.1  

    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

  2. XM_038482843.1 → XP_038338771.1  

    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    4034535..4043435 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038608393.1 → XP_038464321.1  

    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

  2. XM_038608394.1 → XP_038464322.1  

    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    4296844..4305741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038544276.1 → XP_038400204.1  importin-4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MZI1
    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

  2. XM_038544277.1 → XP_038400205.1  importin-4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MZI1
    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    4093204..4102330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005623264.3 → XP_005623321.1  importin-4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MZI1
    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]

  2. XM_022421839.2 → XP_022277547.1  importin-4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MZI1
    Conserved Domains (3) summary
    smart00913
    Location:24 → 90
    IBN_N; Importin-beta N-terminal domain
    COG5215
    Location:357 → 620
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    sd00044
    Location:353 → 381
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
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