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IRF6 interferon regulatory factor 6 [ Canis lupus familiaris (dog) ]

Gene ID: 480015, updated on 27-Jun-2026
Official Symbol
IRF6provided by VGNC
Official Full Name
interferon regulatory factor 6provided by VGNC
Primary source
VGNC:VGNC:42095
See related
Ensembl:ENSCAFG00845002898 RGD:12375639
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See IRF6 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (8148397..8167818, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (8024947..8044365, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (8313202..8332619, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (8078084..8097501, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (8175119..8194534, complement)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene laminin subunit beta 3 Neighboring gene U6 spliceosomal RNA Neighboring gene hydroxysteroid 11-beta dehydrogenase 1 Neighboring gene TRAF3 interacting protein 3 Neighboring gene chromosome 7 C1orf74 homolog Neighboring gene UTP25 small subunit processome component Neighboring gene uncharacterized LOC111096614 Neighboring gene nuclear transport factor 2-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
interferon regulatory factor 6

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    8148397..8167818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038670901.1 → XP_038526829.1  interferon regulatory factor 6

    UniProtKB/TrEMBL
    A0A8C0KK54, A0A8I3MM71
    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

  2. XM_038670900.1 → XP_038526828.1  interferon regulatory factor 6

    UniProtKB/TrEMBL
    A0A8C0KK54, A0A8I3MM71
    Related
    ENSCAFP00845004093.1, ENSCAFT00845005153.1
    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    8078084..8097501 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038480727.1 → XP_038336655.1  

    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

  2. XM_038480726.1 → XP_038336654.1  

    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    8175119..8194534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038606205.1 → XP_038462133.1  

    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

  2. XM_038606204.1 → XP_038462132.1  

    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    8313202..8332619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038542049.1 → XP_038397977.1  interferon regulatory factor 6

    UniProtKB/TrEMBL
    A0A8C0KK54, A0A8I3MM71
    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

  2. XM_038542048.1 → XP_038397976.1  interferon regulatory factor 6

    UniProtKB/TrEMBL
    A0A8C0KK54, A0A8I3MM71
    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8024947..8044365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_537138.7 → XP_537138.3  interferon regulatory factor 6

    See identical proteins and their annotated locations for XP_537138.3

    UniProtKB/TrEMBL
    A0A8C0KK54, A0A8I3MM71
    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3

  2. XM_005622335.4 → XP_005622392.1  interferon regulatory factor 6

    See identical proteins and their annotated locations for XP_005622392.1

    UniProtKB/TrEMBL
    A0A8C0KK54, A0A8I3MM71
    Conserved Domains (2) summary
    pfam00605
    Location:9 → 114
    IRF; Interferon regulatory factor transcription factor
    pfam10401
    Location:219 → 402
    IRF-3; Interferon-regulatory factor 3
Nucleotide Protein
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