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KLHL12 kelch like family member 12 [ Canis lupus familiaris (dog) ]

Gene ID: 479996, updated on 5-Mar-2024

Summary

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Official Symbol
KLHL12provided by VGNC
Official Full Name
kelch like family member 12provided by VGNC
Primary source
VGNC:VGNC:42448
See related
Ensembl:ENSCAFG00845014708
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (266263..293556)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (311438..338723)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (386991..414305)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (254937..282247)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (364012..391323)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096577 Neighboring gene cytochrome b5 reductase 1 Neighboring gene adiponectin receptor 1 Neighboring gene RAB interacting factor Neighboring gene uncharacterized LOC119872474 Neighboring gene tubulin alpha 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
kelch-like protein 12
Names
kelch-like 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    266263..293556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038670682.1 → XP_038526610.1  kelch-like protein 12

    UniProtKB/TrEMBL
    A0A8C0KR93
    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

  2. XM_038670681.1 → XP_038526609.1  kelch-like protein 12

    UniProtKB/TrEMBL
    A0A8C0KR93
    Related
    ENSCAFP00845020780.1, ENSCAFT00845026360.1
    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    254937..282247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038480516.1 → XP_038336444.1  kelch-like protein 12

    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

  2. XM_038480515.1 → XP_038336443.1  kelch-like protein 12

    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    364012..391323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038605972.1 → XP_038461900.1  kelch-like protein 12

    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

  2. XM_038605971.1 → XP_038461899.1  kelch-like protein 12

    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    386991..414305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038541843.1 → XP_038397771.1  kelch-like protein 12

    UniProtKB/TrEMBL
    A0A8C0KR93
    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

  2. XM_038541842.1 → XP_038397770.1  kelch-like protein 12

    UniProtKB/TrEMBL
    A0A8C0KR93
    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    311438..338723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_537119.7 → XP_537119.2  kelch-like protein 12

    See identical proteins and their annotated locations for XP_537119.2

    UniProtKB/TrEMBL
    A0A8C0KR93
    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)

  2. XM_005622174.4 → XP_005622231.1  kelch-like protein 12

    See identical proteins and their annotated locations for XP_005622231.1

    UniProtKB/TrEMBL
    A0A8C0KR93
    Conserved Domains (5) summary
    smart00612
    Location:521 → 565
    Kelch; Kelch domain
    PHA03098
    Location:46 → 501
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:416 → 459
    Kelch; KELCH repeat [structural motif]
    cd18242
    Location:12 → 135
    BTB_POZ_KLHL12_C3IP1_DKIR; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 12 (KLHL12)
    cd18452
    Location:130 → 265
    BACK_KLHL12; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 12 (KLHL12)
Nucleotide Protein
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