U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

DNASE2B deoxyribonuclease 2 beta [ Canis lupus familiaris (dog) ]

Gene ID: 479973, updated on 25-Jul-2026
Official Symbol
DNASE2Bprovided by VGNC
Official Full Name
deoxyribonuclease 2 betaprovided by VGNC
Primary source
VGNC:VGNC:40027
See related
Ensembl:ENSCAFG00845001747 RGD:12134759
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See DNASE2B in Genome Data Viewer
Location:
chromosome: 6
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (64005309..64021750, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (66113707..66130124, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (64008051..64024465, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (63533264..63549678, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (63501952..63518371, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene ribosome production factor 1 homolog Neighboring gene uncharacterized LOC102156327 Neighboring gene uncharacterized LOC119872366 Neighboring gene urate oxidase Neighboring gene sterile alpha motif domain containing 13

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables deoxyribonuclease II activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic DNA fragmentation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
deoxyribonuclease-2-beta
XP_022276285.1
XP_022276286.1
XP_022276287.1
XP_038336382.1

Length

  • 358
XP_038390659.1
XP_038390661.1
XP_038390674.1
XP_038394845.1
XP_038394846.1
XP_038394847.1
XP_038394848.1
XP_038394849.1
XP_038394850.1
XP_038458972.1
XP_038458973.1
XP_038458974.1
XP_038458975.1
XP_038458976.1
XP_038458977.1
XP_038458978.1
XP_038523676.1
XP_038523677.1
XP_038523678.1
XP_038523679.1
XP_038523680.1
XP_038523681.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    64005309..64021750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038667753.1 → XP_038523681.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  2. XM_038667748.1 → XP_038523676.1  deoxyribonuclease-2-beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3RQ66
    Related
    ENSCAFP00845002449.1, ENSCAFT00845003066.1
    Conserved Domains (1) summary
    pfam03265
    Location:29 → 346
    DNase_II; Deoxyribonuclease II

  3. XM_038667752.1 → XP_038523680.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  4. XM_038667750.1 → XP_038523678.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  5. XM_038667751.1 → XP_038523679.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  6. XM_038667749.1 → XP_038523677.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    63533264..63549678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038480454.1 → XP_038336382.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    63501952..63518371 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038603050.1 → XP_038458978.1  

  2. XM_038603044.1 → XP_038458972.1  

  3. XM_038603049.1 → XP_038458977.1  

  4. XM_038603047.1 → XP_038458975.1  

  5. XM_038603048.1 → XP_038458976.1  

  6. XM_038603045.1 → XP_038458973.1  

  7. XM_038603046.1 → XP_038458974.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    64008051..64024465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038538922.1 → XP_038394850.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  2. XM_038538917.1 → XP_038394845.1  deoxyribonuclease-2-beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3RQ66

  3. XM_038538921.1 → XP_038394849.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  4. XM_038538919.1 → XP_038394847.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  5. XM_038538920.1 → XP_038394848.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  6. XM_038538918.1 → XP_038394846.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    66113707..66130124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022420578.2 → XP_022276286.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  2. XM_022420577.2 → XP_022276285.1  deoxyribonuclease-2-beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3RQ66
    Conserved Domains (1) summary
    pfam03265
    Location:27 → 352
    DNase_II; Deoxyribonuclease II

  3. XM_038534746.1 → XP_038390674.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  4. XM_038534733.1 → XP_038390661.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  5. XM_022420579.2 → XP_022276287.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  6. XM_038534731.1 → XP_038390659.1  deoxyribonuclease-2-beta isoform X2

    Conserved Domains (1) summary
    cl15239
    Location:14 → 153
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials