ABAT 4-aminobutyrate aminotransferase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ABATprovided by VGNC
Official Full Name: 4-aminobutyrate aminotransferaseprovided by VGNC
Primary source: VGNC:VGNC:37421
See related: Ensembl:ENSCAFG00000019030
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	6	NC_051810.1 (33584479..33670069, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	6	NC_006588.4 (34776452..34862027, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	6	NC_049227.1 (33678493..33764059, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	6	NC_049266.1 (33386823..33472421, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	6	NC_049747.1 (33256654..33342147, complement)
105	previous assembly	CanFam3.1 (GCF_000002285.3)	6	NC_006588.3 (33385779..33471348, complement)

Chromosome 6 - NC_051810.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

direct involvement of ABAT in pathways affecting lower esophageal sphincter (LES) control in gastro esophageal reflux disease
Title: 4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease.

Submit: New GeneRIF Correction

General gene information

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Homology

Homologs of the ABAT gene: The ABAT gene is conserved in human, chimpanzee, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.
Orthologs from Annotation Pipeline: 345 organisms have orthologs with human gene ABAT
Orthologs

General protein information

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Preferred Names: 4-aminobutyrate aminotransferase, mitochondrial

XP_005621619.1

EC 2.6.1.19

EC 2.6.1.22

XP_022275790.1

EC 2.6.1.19

EC 2.6.1.22

XP_038335112.1

EC 2.6.1.19

EC 2.6.1.22

XP_038335113.1

EC 2.6.1.19

EC 2.6.1.22

XP_038335114.1

EC 2.6.1.19

EC 2.6.1.22

XP_038396337.1

EC 2.6.1.19

EC 2.6.1.22

XP_038396338.1

EC 2.6.1.19

EC 2.6.1.22

XP_038396339.1

EC 2.6.1.19

EC 2.6.1.22

XP_038460438.1

EC 2.6.1.19

EC 2.6.1.22

XP_038460439.1

EC 2.6.1.19

EC 2.6.1.22

XP_038460440.1

EC 2.6.1.19

EC 2.6.1.22

XP_038525124.1

EC 2.6.1.19

EC 2.6.1.22

XP_038525125.1

EC 2.6.1.19

EC 2.6.1.22

XP_038525126.1

EC 2.6.1.19

EC 2.6.1.22

XP_851424.2

EC 2.6.1.19

EC 2.6.1.22

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051810.1 Reference ROS_Cfam_1.0

Range

33584479..33670069 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038669196.1 → XP_038525124.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038669198.1 → XP_038525126.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038669197.1 → XP_038525125.1 4-aminobutyrate aminotransferase, mitochondrial

Alternate UMICH_Zoey_3.1

Genomic

NC_049266.1 Alternate UMICH_Zoey_3.1

Range

33386823..33472421 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038479184.1 → XP_038335112.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038479186.1 → XP_038335114.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038479185.1 → XP_038335113.1 4-aminobutyrate aminotransferase, mitochondrial

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049747.1 Alternate UNSW_CanFamBas_1.0

Range

33256654..33342147 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038604510.1 → XP_038460438.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038604512.1 → XP_038460440.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038604511.1 → XP_038460439.1 4-aminobutyrate aminotransferase, mitochondrial

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049227.1 Alternate UU_Cfam_GSD_1.0

Range

33678493..33764059 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038540409.1 → XP_038396337.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038540411.1 → XP_038396339.1 4-aminobutyrate aminotransferase, mitochondrial
XM_038540410.1 → XP_038396338.1 4-aminobutyrate aminotransferase, mitochondrial

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

34776452..34862027 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_846331.6 → XP_851424.2 4-aminobutyrate aminotransferase, mitochondrial

See identical proteins and their annotated locations for XP_851424.2

UniProtKB/TrEMBL

E2R776

Related

ENSCAFP00000028090.4

Conserved Domains (1) summary

TIGR00699
Location:34 → 496

GABAtrns_euk; 4-aminobutyrate aminotransferase, eukaryotic type
XM_005621562.4 → XP_005621619.1 4-aminobutyrate aminotransferase, mitochondrial

See identical proteins and their annotated locations for XP_005621619.1

UniProtKB/TrEMBL

E2R776

Conserved Domains (1) summary

TIGR00699
Location:34 → 496

GABAtrns_euk; 4-aminobutyrate aminotransferase, eukaryotic type
XM_022420082.2 → XP_022275790.1 4-aminobutyrate aminotransferase, mitochondrial

Conserved Domains (1) summary

TIGR00699
Location:34 → 496

GABAtrns_euk; 4-aminobutyrate aminotransferase, eukaryotic type