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LRWD1 leucine rich repeats and WD repeat domain containing 1 [ Canis lupus familiaris (dog) ]

Gene ID: 479725, updated on 25-Jul-2026
Official Symbol
LRWD1provided by VGNC
Official Full Name
leucine rich repeats and WD repeat domain containing 1provided by VGNC
Primary source
VGNC:VGNC:42835
See related
Ensembl:ENSCAFG00845004759 RGD:12324830
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See LRWD1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (7531220..7537350, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (9406064..9412193, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (7626509..7632639, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (7499730..7505854, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (7462794..7468922, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene RAS p21 protein activator 4B Neighboring gene RNA polymerase II subunit J Neighboring gene alkB homolog 4, lysine demethylase Neighboring gene ORAI calcium release-activated calcium modulator 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of protein localization to chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of nuclear origin of replication recognition complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
leucine-rich repeat and WD repeat-containing protein 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    7531220..7537350 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038667959.1 → XP_038523887.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KK71
    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:242 → 285
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 140
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:334 → 533
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038667957.1 → XP_038523885.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KJT9, A0A8C0KK71, A0A8I3MRC9
    Related
    ENSCAFP00845006742.1, ENSCAFT00845008543.1
    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:288 → 331
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 140
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:380 → 579
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_038667960.1 → XP_038523888.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KK71
    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:203 → 246
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 116
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:295 → 494
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_038667958.1 → XP_038523886.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KK71
    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:249 → 292
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 112
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:341 → 540
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    7499730..7505854 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038477926.1 → XP_038333854.1  

    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:242 → 285
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 140
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:334 → 533
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038477924.1 → XP_038333852.1  

    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:288 → 331
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 140
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:380 → 579
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_038477927.1 → XP_038333855.1  

    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:203 → 246
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 116
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:295 → 494
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_038477925.1 → XP_038333853.1  

    Conserved Domains (4) summary
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:249 → 292
    7WD40; WD40 repeat [structural motif]
    cd21340
    Location:29 → 112
    PPP1R42; protein phosphatase 1 regulatory subunit 42
    cl29593
    Location:341 → 540
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    7462794..7468922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038603259.1 → XP_038459187.1  

  2. XM_038603257.1 → XP_038459185.1  

  3. XM_038603260.1 → XP_038459188.1  

  4. XM_038603258.1 → XP_038459186.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    7626509..7632639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038539175.1 → XP_038395103.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KK71

  2. XM_038539172.1 → XP_038395100.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KK71

  3. XM_038539174.1 → XP_038395102.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KK71

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    9406064..9412193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022419598.1 → XP_022275306.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KK71
    Conserved Domains (4) summary
    COG4886
    Location:15 → 121
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    sd00039
    Location:242 → 285
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:334 → 533
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_536851.5 → XP_536851.3  leucine-rich repeat and WD repeat-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KK71
    Conserved Domains (6) summary
    COG2319
    Location:237 → 579
    WD40; WD40 repeat [General function prediction only]
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:47 → 87
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:22 → 81
    LRR_8; Leucine rich repeat
    sd00039
    Location:288 → 331
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:380 → 579
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_005620992.4 → XP_005621049.1  leucine-rich repeat and WD repeat-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KK71
    Conserved Domains (6) summary
    COG2319
    Location:198 → 540
    WD40; WD40 repeat [General function prediction only]
    sd00031
    Location:23 → 48
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:47 → 87
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:22 → 81
    LRR_8; Leucine rich repeat
    sd00039
    Location:249 → 292
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:341 → 540
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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