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DNAJC21 DnaJ heat shock protein family (Hsp40) member C21 [ Canis lupus familiaris (dog) ]

Gene ID: 479364, updated on 25-Jul-2026
Official Symbol
DNAJC21provided by VGNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member C21provided by VGNC
Primary source
VGNC:VGNC:111443
See related
Ensembl:ENSCAFG00845000877 RGD:12131244
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See DNAJC21 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (73833571..73877695, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (72944316..72988410, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (74238074..74282180, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (73581230..73625321, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (73704791..73748986, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871597 Neighboring gene prolactin receptor Neighboring gene alanine--glyoxylate aminotransferase 2 Neighboring gene biogenesis of ribosomes BRX1 Neighboring gene RAD1 checkpoint DNA exonuclease Neighboring gene uncharacterized LOC119881466 Neighboring gene U6 spliceosomal RNA Neighboring gene tetratricopeptide repeat domain 23 like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dnaJ homolog subfamily C member 21

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    73833571..73877695 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663947.1 → XP_038519875.1  dnaJ homolog subfamily C member 21 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KW93, A0A8I3MX99
    Related
    ENSCAFP00845001153.1, ENSCAFT00845001472.1
    Conserved Domains (4) summary
    COG5269
    Location:4 → 269
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    PRK10767
    Location:2 → 66
    PRK10767; chaperone protein DnaJ; Provisional
    sd00020
    Location:316 → 338
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:314 → 339
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  2. XM_038663946.1 → XP_038519874.1  dnaJ homolog subfamily C member 21 isoform X1

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

RNA

  1. XR_005426216.1 RNA Sequence

  2. XR_005426215.1 RNA Sequence

  3. XR_005426214.1 RNA Sequence

  4. XR_005426213.1 RNA Sequence

  5. XR_005426211.1 RNA Sequence

  6. XR_005426210.1 RNA Sequence

  7. XR_005426212.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    73581230..73625321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474231.1 → XP_038330159.1  

    Conserved Domains (4) summary
    COG5269
    Location:4 → 269
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    PRK10767
    Location:2 → 66
    PRK10767; chaperone protein DnaJ; Provisional
    sd00020
    Location:316 → 338
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:314 → 339
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  2. XM_038474230.1 → XP_038330158.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

RNA

  1. XR_005324813.1 RNA Sequence

  2. XR_005324812.1 RNA Sequence

  3. XR_005324811.1 RNA Sequence

  4. XR_005324810.1 RNA Sequence

  5. XR_005324808.1 RNA Sequence

  6. XR_005324807.1 RNA Sequence

  7. XR_005324809.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    73704791..73748986 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599632.1 → XP_038455560.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  2. XM_038599630.1 → XP_038455558.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  3. XM_038599629.1 → XP_038455557.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  4. XM_038599628.1 → XP_038455556.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  5. XM_038599627.1 → XP_038455555.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  6. XM_038599626.1 → XP_038455554.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  7. XM_038599625.1 → XP_038455553.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  8. XM_038599623.1 → XP_038455551.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  9. XM_038599633.1 → XP_038455561.1  

    Conserved Domains (4) summary
    COG5269
    Location:4 → 269
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    PRK10767
    Location:2 → 66
    PRK10767; chaperone protein DnaJ; Provisional
    sd00020
    Location:316 → 338
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:314 → 339
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  10. XM_038599624.1 → XP_038455552.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  11. XM_038599631.1 → XP_038455559.1  

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    74238074..74282180 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535357.1 → XP_038391285.1  dnaJ homolog subfamily C member 21 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KW93, A0A8I3MX99
    Conserved Domains (4) summary
    COG5269
    Location:4 → 269
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    PRK10767
    Location:2 → 66
    PRK10767; chaperone protein DnaJ; Provisional
    sd00020
    Location:316 → 338
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:314 → 339
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  2. XM_038535356.1 → XP_038391284.1  dnaJ homolog subfamily C member 21 isoform X1

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

RNA

  1. XR_005358602.1 RNA Sequence

  2. XR_005358601.1 RNA Sequence

  3. XR_005358600.1 RNA Sequence

  4. XR_005358599.1 RNA Sequence

  5. XR_005358597.1 RNA Sequence

  6. XR_005358596.1 RNA Sequence

  7. XR_005358598.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    72944316..72988410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005619400.3 → XP_005619457.1  dnaJ homolog subfamily C member 21 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KW93, A0A8I3MX99
    Conserved Domains (4) summary
    COG5269
    Location:4 → 269
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    PRK10767
    Location:2 → 66
    PRK10767; chaperone protein DnaJ; Provisional
    sd00020
    Location:316 → 338
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:314 → 339
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  2. XM_022417933.2 → XP_022273641.1  dnaJ homolog subfamily C member 21 isoform X1

    Conserved Domains (3) summary
    COG5269
    Location:44 → 283
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    sd00020
    Location:330 → 352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:328 → 353
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

RNA

  1. XR_005339286.1 RNA Sequence

  2. XR_005339285.1 RNA Sequence

  3. XR_005339281.1 RNA Sequence

  4. XR_005339277.1 RNA Sequence

  5. XR_002626121.2 RNA Sequence

  6. XR_005339276.1 RNA Sequence

  7. XR_002626122.2 RNA Sequence

Nucleotide Protein
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