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PSAP prosaposin [ Canis lupus familiaris (dog) ]

Gene ID: 479240, updated on 25-Jul-2026
Official Symbol
PSAPprovided by VGNC
Official Full Name
prosaposinprovided by VGNC
Primary source
VGNC:VGNC:45080
See related
Ensembl:ENSCAFG00845004604 RGD:12386781
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See PSAP in Genome Data Viewer
Location:
chromosome: 4
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (22847636..22880854, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (22708767..22741495, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (23306841..23339591, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (22753725..22786399, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (22952336..22985298, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene cadherin related 23 Neighboring gene chromosome 4 C10orf105 homolog Neighboring gene V-set immunoregulatory receptor Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC119871469 Neighboring gene RNA-binding motif protein, X chromosome-like Neighboring gene carbohydrate sulfotransferase 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in sphingolipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
prosaposin
Names
prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)
XP_038329126.1

Length

  • 527

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    22847636..22880854 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662850.1 → XP_038518778.1  prosaposin isoform X3

    UniProtKB/TrEMBL
    A0A8C0R7L6, A0A8I3MQM8
    Related
    ENSCAFP00845006476.1, ENSCAFT00845008238.1
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:315 → 388
    SapB; Saposin (B) Domains
    pfam02199
    Location:492 → 524
    SapA; Saposin A-type domain

  2. XM_038662849.1 → XP_038518777.1  prosaposin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:317 → 390
    SapB; Saposin (B) Domains
    pfam02199
    Location:494 → 526
    SapA; Saposin A-type domain

  3. XM_038662848.1 → XP_038518776.1  prosaposin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:318 → 391
    SapB; Saposin (B) Domains
    pfam02199
    Location:495 → 527
    SapA; Saposin A-type domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    22753725..22786399 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473198.1 → XP_038329126.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    22952336..22985298 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038598578.1 → XP_038454506.1  

  2. XM_038598577.1 → XP_038454505.1  

  3. XM_038598576.1 → XP_038454504.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    23306841..23339591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534263.1 → XP_038390191.1  prosaposin isoform X3

    UniProtKB/TrEMBL
    A0A8C0R7L6, A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:315 → 388
    SapB; Saposin (B) Domains
    pfam02199
    Location:492 → 524
    SapA; Saposin A-type domain

  2. XM_038534262.1 → XP_038390190.1  prosaposin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:317 → 390
    SapB; Saposin (B) Domains
    pfam02199
    Location:494 → 526
    SapA; Saposin A-type domain

  3. XM_038534261.1 → XP_038390189.1  prosaposin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:318 → 391
    SapB; Saposin (B) Domains
    pfam02199
    Location:495 → 527
    SapA; Saposin A-type domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    22708767..22741495 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005618993.4 → XP_005619050.1  prosaposin isoform X3

    UniProtKB/TrEMBL
    A0A8C0R7L6, A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:315 → 388
    SapB; Saposin (B) Domains
    pfam02199
    Location:492 → 524
    SapA; Saposin A-type domain

  2. XM_005618992.4 → XP_005619049.1  prosaposin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:317 → 390
    SapB; Saposin (B) Domains
    pfam02199
    Location:494 → 526
    SapA; Saposin A-type domain

  3. XM_856497.6 → XP_861590.1  prosaposin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MQM8
    Conserved Domains (3) summary
    smart00162
    Location:21 → 54
    SAPA; Saposin/surfactant protein-B A-type DOMAIN
    smart00741
    Location:318 → 391
    SapB; Saposin (B) Domains
    pfam02199
    Location:495 → 527
    SapA; Saposin A-type domain
Nucleotide Protein
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