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LGALS8 galectin 8 [ Canis lupus familiaris (dog) ]

Gene ID: 479193, updated on 25-Jul-2026
Official Symbol
LGALS8provided by VGNC
Official Full Name
galectin 8provided by VGNC
Primary source
VGNC:VGNC:42650
See related
Ensembl:ENSCAFG00845002813 RGD:12420951
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
galectin-8
Orthologs
all
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Try the new Transcripts and proteins table
See LGALS8 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (3568616..3602071, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (3596286..3613691, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (3920489..3937943, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (3583330..3600748, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (3700220..3717655, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene HEAT repeat containing 1 Neighboring gene EDAR associated death domain Neighboring gene 39S ribosomal protein L22, mitochondrial-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Galectin-8 regulates targeting of Gp135/podocalyxin and lumen formation at the apical surface of renal epithelial cells. Lim H, et al. FASEB J, 2017 Nov. PMID 28747404
  2. Identification and characterization of endogenous galectins expressed in Madin Darby canine kidney cells. Poland PA, et al. J Biol Chem, 2011 Feb 25. PMID 21127048, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results reveal a new role of Gal-8 in the development of luminal organs by regulating targeting of apical polarity protein Gp135
    Title: Galectin-8 regulates targeting of Gp135/podocalyxin and lumen formation at the apical surface of renal epithelial cells.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
galectin-8
Names
lectin, galactoside-binding, soluble, 8 (galectin 8)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284486.1 → NP_001271415.1  galectin-8

    See identical proteins and their annotated locations for NP_001271415.1

    Status: PROVISIONAL

    Source sequence(s)
    HQ637389
    UniProtKB/TrEMBL
    A0A8C0LUH8, A0A8I3RQZ8, E5Q8W8
    Related
    ENSCAFP00845004061.1, ENSCAFT00845005104.1
    Conserved Domains (2) summary
    smart00908
    Location:194 → 313
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    3568616..3602071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662280.1 → XP_038518208.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  2. XM_038662283.1 → XP_038518211.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  3. XM_038662281.1 → XP_038518209.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  4. XM_038662282.1 → XP_038518210.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  5. XM_038662279.1 → XP_038518207.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  6. XM_038662277.1 → XP_038518205.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Related
    ENSCAFP00845004027.1, ENSCAFT00845005058.1
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  7. XM_038662278.1 → XP_038518206.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  8. XM_038662285.1 → XP_038518213.1  galectin-8 isoform X3

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Related
    ENSCAFP00845004032.1, ENSCAFT00845005068.1
    Conserved Domains (2) summary
    smart00908
    Location:216 → 335
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  9. XM_038662276.1 → XP_038518204.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  10. XM_038662287.1 → XP_038518215.1  galectin-8 isoform X5

    UniProtKB/TrEMBL
    A0A8C0LTA6
    Conserved Domains (2) summary
    smart00908
    Location:175 → 294
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  11. XM_038662286.1 → XP_038518214.1  galectin-8 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LUH8, A0A8I3RQZ8, E5Q8W8
    Related
    ENSCAFP00845004040.1, ENSCAFT00845005080.1
    Conserved Domains (2) summary
    smart00908
    Location:194 → 313
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  12. XM_038662275.1 → XP_038518203.1  galectin-8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RSH0
    Conserved Domains (2) summary
    smart00908
    Location:235 → 354
    Gal-bind_lectin; Galactoside-binding lectin
    pfam00337
    Location:17 → 150
    Gal-bind_lectin; Galactoside-binding lectin

  13. XM_038662284.1 → XP_038518212.1  galectin-8 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MK80
    Related
    ENSCAFP00845003996.1, ENSCAFT00845005013.1
    Conserved Domains (1) summary
    smart00908
    Location:226 → 345
    Gal-bind_lectin; Galactoside-binding lectin

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    3583330..3600748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    3700220..3717655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    3920489..3937943 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    3596286..3613691 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
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