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IDH2 isocitrate dehydrogenase (NADP(+)) 2 [ Canis lupus familiaris (dog) ]

Gene ID: 479043, updated on 17-Aug-2024

Summary

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Official Symbol
IDH2provided by VGNC
Official Full Name
isocitrate dehydrogenase (NADP(+)) 2provided by VGNC
Primary source
VGNC:VGNC:53183
See related
Ensembl:ENSCAFG00845000909
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See IDH2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (53486432..53502992, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (55708523..55724976, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (53558279..53574816, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (53006922..53023434, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (53217752..53234294, complement)

Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095225 Neighboring gene actin related protein 2/3 complex inhibitor Neighboring gene zinc finger protein 710 Neighboring gene uncharacterized LOC111095226 Neighboring gene semaphorin 4B Neighboring gene GDP-D-glucose phosphorylase 1 Neighboring gene calcium and integrin binding 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional alteration of canine isocitrate dehydrogenase 2 (IDH2) via an R174K mutation. Kawakami S, et al. J Vet Med Sci, 2018 Jan 27. PMID 29162772, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables isocitrate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in isocitrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
isocitrate dehydrogenase [NADP], mitochondrial; LOW QUALITY PROTEIN: isocitrate dehydrogenase [NADP], mitochondrial
Names
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
XP_038327851.1
XP_038331210.1
XP_038388781.1
XP_038453104.1
XP_038517286.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051807.1 Reference ROS_Cfam_1.0

    Range
    53486432..53502992 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038661358.1 → XP_038517286.1  isocitrate dehydrogenase [NADP], mitochondrial

    UniProtKB/TrEMBL
    A0A2Z5XAD4, A0A8C0R241, A0A8P0NE04
    Related
    ENSCAFP00845001268.1, ENSCAFT00845001600.1
    Conserved Domains (1) summary
    PTZ00435
    Location:41 → 453
    PTZ00435; isocitrate dehydrogenase; Provisional

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049263.1 Alternate UMICH_Zoey_3.1

    Range
    53006922..53023434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038471923.1 → XP_038327851.1  isocitrate dehydrogenase [NADP], mitochondrial

    Conserved Domains (1) summary
    PTZ00435
    Location:41 → 453
    PTZ00435; isocitrate dehydrogenase; Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

    Range
    53217752..53234294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038597176.1 → XP_038453104.1  isocitrate dehydrogenase [NADP], mitochondrial

    Conserved Domains (1) summary
    PTZ00435
    Location:41 → 453
    PTZ00435; isocitrate dehydrogenase; Provisional

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

    Range
    53558279..53574816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038532853.1 → XP_038388781.1  isocitrate dehydrogenase [NADP], mitochondrial

    UniProtKB/TrEMBL
    A0A2Z5XAD4, A0A8C0R241, A0A8P0NE04
    Conserved Domains (1) summary
    PTZ00435
    Location:41 → 453
    PTZ00435; isocitrate dehydrogenase; Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    55708523..55724976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475282.1 → XP_038331210.1  LOW QUALITY PROTEIN: isocitrate dehydrogenase [NADP], mitochondrial

    UniProtKB/TrEMBL
    A0A8P0NE04
    Conserved Domains (1) summary
    PTZ00435
    Location:41 → 453
    PTZ00435; isocitrate dehydrogenase; Provisional
Nucleotide Protein
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