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KPNA4 karyopherin subunit alpha 4 [ Canis lupus familiaris (dog) ]

Gene ID: 478680, updated on 25-Jul-2026
Official Symbol
KPNA4provided by VGNC
Official Full Name
karyopherin subunit alpha 4provided by VGNC
Primary source
VGNC:VGNC:42502
See related
Ensembl:ENSCAFG00845027853 RGD:12136591
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See KPNA4 in Genome Data Viewer
Location:
chromosome: 34
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (26605763..26671157, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (30591206..30656539, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (26735945..26801570, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (26535571..26600913, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (26495988..26561625, complement)

Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106558222 Neighboring gene tripartite motif containing 59 Neighboring gene uncharacterized LOC119867514 Neighboring gene small Cajal body-specific RNA 7 Neighboring gene malate dehydrogenase, mitochondrial-like Neighboring gene ADP-ribosylation factor-like protein 14 Neighboring gene ARF like GTPase 14

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear import signal receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in NLS-bearing protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
importin subunit alpha-3

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051838.1 Reference ROS_Cfam_1.0

    Range
    26605763..26671157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445941.1 → XP_038301869.1  importin subunit alpha-3

    UniProtKB/TrEMBL
    A0A8I3QF14
    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

  2. XM_038445940.1 → XP_038301868.1  importin subunit alpha-3

    UniProtKB/TrEMBL
    A0A8I3QF14
    Related
    ENSCAFP00845038634.1, ENSCAFT00845049232.1
    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049294.1 Alternate UMICH_Zoey_3.1

    Range
    26535571..26600913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038520136.1 → XP_038376064.1  

    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

  2. XM_038520135.1 → XP_038376063.1  

    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

    Range
    26495988..26561625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038648179.1 → XP_038504107.1  

    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

  2. XM_038648178.1 → XP_038504106.1  

    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

    Range
    26735945..26801570 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583766.1 → XP_038439694.1  importin subunit alpha-3

    UniProtKB/TrEMBL
    A0A8I3QF14
    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

  2. XM_038583765.1 → XP_038439693.1  importin subunit alpha-3

    UniProtKB/TrEMBL
    A0A8I3QF14
    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30591206..30656539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022414075.2 → XP_022269783.1  importin subunit alpha-3

    UniProtKB/TrEMBL
    A0A8I3QF14
    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]

  2. XM_005639865.4 → XP_005639922.1  importin subunit alpha-3

    See identical proteins and their annotated locations for XP_005639922.1

    UniProtKB/TrEMBL
    A0A8I3QF14
    Conserved Domains (2) summary
    COG5064
    Location:11 → 513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:279 → 311
    ARM; armadillo repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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