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P3H2 prolyl 3-hydroxylase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 478674, updated on 5-Sep-2025
Official Symbol
P3H2provided by VGNC
Official Full Name
prolyl 3-hydroxylase 2provided by VGNC
Primary source
VGNC:VGNC:44220
See related
Ensembl:ENSCAFG00845023995 RGD:12184798
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
LEPREL1
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See P3H2 in Genome Data Viewer
Location:
chromosome: 34
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (21969192..22119559, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (26128347..26278616, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (22219915..22370251, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (21984404..22141097, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (21977205..22127973, complement)

Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene tumor protein p63 Neighboring gene uncharacterized LOC111093957 Neighboring gene uncharacterized LOC119867446 Neighboring gene uncharacterized LOC111093933

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables procollagen-proline 3-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
prolyl 3-hydroxylase 2
Names
leprecan-like 1
XP_038301796.1
XP_038375995.1
XP_038439620.1
XP_038504036.1

Length

  • 704
XP_535843.2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051838.1 Reference ROS_Cfam_1.0

    Range
    21969192..22119559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445868.1 → XP_038301796.1  prolyl 3-hydroxylase 2

    UniProtKB/TrEMBL
    A0A8C0L6W3, A0A8C0NYE6, A0A8C0T681, A0A8I3PG73
    Related
    ENSCAFP00845033230.1, ENSCAFT00845042385.1
    Conserved Domains (2) summary
    smart00702
    Location:473 → 671
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    TIGR03302
    Location:315 → 376
    OM_YfiO; outer membrane assembly lipoprotein YfiO

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049294.1 Alternate UMICH_Zoey_3.1

    Range
    21984404..22141097 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038520067.1 → XP_038375995.1  prolyl 3-hydroxylase 2

    Conserved Domains (2) summary
    smart00702
    Location:473 → 671
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    TIGR03302
    Location:315 → 376
    OM_YfiO; outer membrane assembly lipoprotein YfiO

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

    Range
    21977205..22127973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038648108.1 → XP_038504036.1  prolyl 3-hydroxylase 2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

    Range
    22219915..22370251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583692.1 → XP_038439620.1  prolyl 3-hydroxylase 2

    UniProtKB/TrEMBL
    A0A8C0L6W3, A0A8C0NYE6, A0A8C0T681, A0A8I3PG73
    Conserved Domains (2) summary
    smart00702
    Location:473 → 671
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    TIGR03302
    Location:315 → 376
    OM_YfiO; outer membrane assembly lipoprotein YfiO

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    26128347..26278616 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535843.7 → XP_535843.2  prolyl 3-hydroxylase 2

    UniProtKB/TrEMBL
    A0A8C0L6W3, A0A8C0NYE6, A0A8C0T681, A0A8I3PG73
    Conserved Domains (2) summary
    smart00702
    Location:473 → 671
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    TIGR03302
    Location:315 → 376
    OM_YfiO; outer membrane assembly lipoprotein YfiO
Nucleotide Protein
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