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MARCHF6 membrane associated ring-CH-type finger 6 [ Canis lupus familiaris (dog) ]

Gene ID: 478617, updated on 25-Jul-2026
Official Symbol
MARCHF6provided by VGNC
Official Full Name
membrane associated ring-CH-type finger 6provided by VGNC
Primary source
VGNC:VGNC:43019
See related
Ensembl:ENSCAFG00845021339 RGD:12220150
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
MARCH6
Orthologs
all
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Try the new Transcripts and proteins table
See MARCHF6 in Genome Data Viewer
Location:
chromosome: 34
Exon count:
29
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (3785457..3868858, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (8383624..8466476, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (4044972..4127896, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (3835287..3918110, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (3813874..3897483, complement)

Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene rhophilin associated tail protein 1 like Neighboring gene uncharacterized LOC119867469 Neighboring gene uncharacterized LOC119867419 Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene carboxymethylenebutenolidase homolog

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein ligase MARCHF6
XP_005639724.1
XP_022269900.1
XP_022269901.1
XP_022269902.1
XP_038301415.1
XP_038301416.1
XP_038301417.1
XP_038301418.1
XP_038301419.1
XP_038318815.1
XP_038375596.1
XP_038375598.1
XP_038375599.1
XP_038375600.1
XP_038375601.1
XP_038439246.1
XP_038439247.1
XP_038439248.1
XP_038439249.1
XP_038439250.1
XP_038503654.1
XP_038503655.1
XP_038503658.1
XP_038503659.1
XP_038503660.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051838.1 Reference ROS_Cfam_1.0

    Range
    3785457..3868858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445490.1 → XP_038301418.1  E3 ubiquitin-protein ligase MARCHF6 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Related
    ENSCAFP00845029623.1, ENSCAFT00845037806.1
    Conserved Domains (1) summary
    cd16702
    Location:8 → 57
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  2. XM_038445491.1 → XP_038301419.1  E3 ubiquitin-protein ligase MARCHF6 isoform X5

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Related
    ENSCAFP00845029754.1, ENSCAFT00845037969.1
    Conserved Domains (1) summary
    COG5183
    Location:314 → 845
    SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]

  3. XM_038445489.1 → XP_038301417.1  E3 ubiquitin-protein ligase MARCHF6 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:10 → 59
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  4. XM_038445488.1 → XP_038301416.1  E3 ubiquitin-protein ligase MARCHF6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  5. XM_038445487.1 → XP_038301415.1  E3 ubiquitin-protein ligase MARCHF6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049294.1 Alternate UMICH_Zoey_3.1

    Range
    3835287..3918110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038519672.1 → XP_038375600.1  

    Conserved Domains (1) summary
    cd16702
    Location:8 → 57
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  2. XM_038519673.1 → XP_038375601.1  

    Conserved Domains (1) summary
    COG5183
    Location:314 → 845
    SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]

  3. XM_038519671.1 → XP_038375599.1  

    Conserved Domains (1) summary
    cd16702
    Location:10 → 59
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  4. XM_038519670.1 → XP_038375598.1  

    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  5. XM_038519668.1 → XP_038375596.1  

    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

    Range
    3813874..3897483 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038647731.1 → XP_038503659.1  

    Conserved Domains (1) summary
    cd16702
    Location:8 → 57
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  2. XM_038647732.1 → XP_038503660.1  

    Conserved Domains (1) summary
    COG5183
    Location:314 → 845
    SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]

  3. XM_038647730.1 → XP_038503658.1  

    Conserved Domains (1) summary
    cd16702
    Location:10 → 59
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  4. XM_038647727.1 → XP_038503655.1  

    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  5. XM_038647726.1 → XP_038503654.1  

    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

    Range
    4044972..4127896 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583321.1 → XP_038439249.1  E3 ubiquitin-protein ligase MARCHF6 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:8 → 57
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  2. XM_038583322.1 → XP_038439250.1  E3 ubiquitin-protein ligase MARCHF6 isoform X5

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    COG5183
    Location:314 → 845
    SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]

  3. XM_038583320.1 → XP_038439248.1  E3 ubiquitin-protein ligase MARCHF6 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:10 → 59
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  4. XM_038583319.1 → XP_038439247.1  E3 ubiquitin-protein ligase MARCHF6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  5. XM_038583318.1 → XP_038439246.1  E3 ubiquitin-protein ligase MARCHF6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8383624..8466476 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038462887.1 → XP_038318815.1  E3 ubiquitin-protein ligase MARCHF6 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:8 → 57
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  2. XM_022414194.2 → XP_022269902.1  E3 ubiquitin-protein ligase MARCHF6 isoform X5

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    COG5183
    Location:314 → 845
    SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]

  3. XM_022414193.2 → XP_022269901.1  E3 ubiquitin-protein ligase MARCHF6 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:10 → 59
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  4. XM_005639667.4 → XP_005639724.1  E3 ubiquitin-protein ligase MARCHF6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)

  5. XM_022414192.2 → XP_022269900.1  E3 ubiquitin-protein ligase MARCHF6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFG4
    Conserved Domains (1) summary
    cd16702
    Location:15 → 64
    RING_CH-C4HC3_MARCH6; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH6 (MARCH6)
Nucleotide Protein
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