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PCYT1A phosphate cytidylyltransferase 1A, choline [ Canis lupus familiaris (dog) ]

Gene ID: 478600, updated on 25-Jul-2026
Official Symbol
PCYT1Aprovided by VGNC
Official Full Name
phosphate cytidylyltransferase 1A, cholineprovided by VGNC
Primary source
VGNC:VGNC:44329
See related
Ensembl:ENSCAFG00845029954 RGD:12058604
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See PCYT1A in Genome Data Viewer
Location:
chromosome: 33
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (29596717..29648017, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (29387581..29438871, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (30060502..30111773, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (29386580..29435254, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (29437747..29489070, complement)

Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 19 Neighboring gene high mobility group protein B3-like Neighboring gene solute carrier family 51 member A Neighboring gene uncharacterized LOC119867351 Neighboring gene dynein light chain Tctex-type 2B Neighboring gene UBX domain protein 7 Neighboring gene uncharacterized LOC119867352

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The rate-limiting enzyme in phosphatidylcholine synthesis is associated with nuclear speckles under stress conditions. Favale NO, et al. Biochim Biophys Acta, 2010 Nov. PMID 20647050
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the intranuclear organelle distribution of CCTalpha is a novel mechanism for the regulation of enzyme activity
    Title: The rate-limiting enzyme in phosphatidylcholine synthesis is associated with nuclear speckles under stress conditions.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables choline-phosphate cytidylyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylcholine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in CDP-choline pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
choline-phosphate cytidylyltransferase A
Names
phosphate cytidylyltransferase 1, choline, alpha
XP_005639655.1
XP_005639656.1
XP_038301185.1
XP_038301186.1
XP_038301187.1
XP_038375419.1
XP_038375420.1
XP_038375421.1
XP_038439059.1
XP_038439060.1
XP_038439061.1
XP_038503477.1
XP_038503478.1
XP_038503479.1
XP_535776.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051837.1 Reference ROS_Cfam_1.0

    Range
    29596717..29648017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445257.1 → XP_038301185.1  choline-phosphate cytidylyltransferase A

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Related
    ENSCAFP00845041685.1, ENSCAFT00845053090.1
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  2. XM_038445258.1 → XP_038301186.1  choline-phosphate cytidylyltransferase A

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Related
    ENSCAFP00845041678.1, ENSCAFT00845053081.1
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  3. XM_038445259.1 → XP_038301187.1  choline-phosphate cytidylyltransferase A

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Related
    ENSCAFP00845041692.1, ENSCAFT00845053098.1
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049293.1 Alternate UMICH_Zoey_3.1

    Range
    29386580..29435254 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038519492.1 → XP_038375420.1  

    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  2. XM_038519493.1 → XP_038375421.1  

    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  3. XM_038519491.1 → XP_038375419.1  

    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

    Range
    29437747..29489070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038647549.1 → XP_038503477.1  

    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  2. XM_038647550.1 → XP_038503478.1  

    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  3. XM_038647551.1 → XP_038503479.1  

    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

    Range
    30060502..30111773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583131.1 → XP_038439059.1  choline-phosphate cytidylyltransferase A

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  2. XM_038583132.1 → XP_038439060.1  choline-phosphate cytidylyltransferase A

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  3. XM_038583133.1 → XP_038439061.1  choline-phosphate cytidylyltransferase A

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    29387581..29438871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535776.7 → XP_535776.1  choline-phosphate cytidylyltransferase A

    See identical proteins and their annotated locations for XP_535776.1

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  2. XM_005639598.4 → XP_005639655.1  choline-phosphate cytidylyltransferase A

    See identical proteins and their annotated locations for XP_005639655.1

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase

  3. XM_005639599.4 → XP_005639656.1  choline-phosphate cytidylyltransferase A

    See identical proteins and their annotated locations for XP_005639656.1

    UniProtKB/TrEMBL
    A0A8C0JPN3, A0A8I3Q529, A0A8I3QLF2
    Conserved Domains (1) summary
    cd02174
    Location:75 → 224
    CCT; CTP:phosphocholine cytidylyltransferase
Nucleotide Protein
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