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UNC5C unc-5 netrin receptor C [ Canis lupus familiaris (dog) ]

Gene ID: 478485, updated on 25-Jul-2026
Official Symbol
UNC5Cprovided by VGNC
Official Full Name
unc-5 netrin receptor Cprovided by VGNC
Primary source
VGNC:VGNC:48141
See related
Ensembl:ENSCAFG00845022086 RGD:12430792
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See UNC5C in Genome Data Viewer
Location:
chromosome: 32
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (18164222..18513849, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (23609404..23959891)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (21584814..21936742)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (18134124..18485245, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (17955873..18306960, complement)

Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093605 Neighboring gene uncharacterized LOC111093606 Neighboring gene bone morphogenetic protein receptor type 1B Neighboring gene uncharacterized LOC111093628 Neighboring gene U4 spliceosomal RNA Neighboring gene nuclear transport factor 2-like Neighboring gene uncharacterized LOC111095027 Neighboring gene pyruvate dehydrogenase E1 subunit alpha 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables netrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in netrin-activated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
netrin receptor UNC5C
Names
unc-5 homolog C

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051836.1 Reference ROS_Cfam_1.0

    Range
    18164222..18513849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038444174.1 → XP_038300102.1  netrin receptor UNC5C isoform X2

    UniProtKB/TrEMBL
    A0A8C0JT61, A0A8I3PFL2, A0A8I3S2Y3
    Related
    ENSCAFP00845030666.1, ENSCAFT00845039156.1
    Conserved Domains (6) summary
    smart00218
    Location:528 → 631
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:678 → 817
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:844 → 926
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_038444173.1 → XP_038300101.1  netrin receptor UNC5C isoform X1

    UniProtKB/TrEMBL
    A0A8C0JQH3, A0A8I3PF54, A0A8I3PFL2
    Related
    ENSCAFP00845030555.1, ENSCAFT00845039007.1
    Conserved Domains (6) summary
    smart00218
    Location:547 → 650
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:697 → 836
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:863 → 945
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_038444175.1 → XP_038300103.1  netrin receptor UNC5C isoform X3

    UniProtKB/TrEMBL
    A0A8C0JU44
    Conserved Domains (6) summary
    smart00218
    Location:364 → 467
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:80 → 131
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:514 → 653
    UPA; UPA domain
    cd00096
    Location:16 → 20
    Ig; Ig strand C [structural motif]
    cl11960
    Location:16 → 74
    Ig; Immunoglobulin domain
    cl14633
    Location:680 → 762
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049292.1 Alternate UMICH_Zoey_3.1

    Range
    18134124..18485245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038518565.1 → XP_038374493.1  

    Conserved Domains (6) summary
    smart00218
    Location:528 → 631
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:678 → 817
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:844 → 926
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_038518564.1 → XP_038374492.1  

    Conserved Domains (6) summary
    smart00218
    Location:547 → 650
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:697 → 836
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:863 → 945
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_038518566.1 → XP_038374494.1  

    Conserved Domains (6) summary
    smart00218
    Location:364 → 467
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:80 → 131
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:514 → 653
    UPA; UPA domain
    cd00096
    Location:16 → 20
    Ig; Ig strand C [structural motif]
    cl11960
    Location:16 → 74
    Ig; Immunoglobulin domain
    cl14633
    Location:680 → 762
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

    Range
    17955873..18306960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038646511.1 → XP_038502439.1  

    Conserved Domains (6) summary
    smart00218
    Location:528 → 631
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:678 → 817
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:844 → 926
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_038646510.1 → XP_038502438.1  

    Conserved Domains (6) summary
    smart00218
    Location:547 → 650
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:697 → 836
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:863 → 945
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_038646512.1 → XP_038502440.1  

    Conserved Domains (6) summary
    smart00218
    Location:364 → 467
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:80 → 131
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:514 → 653
    UPA; UPA domain
    cd00096
    Location:16 → 20
    Ig; Ig strand C [structural motif]
    cl11960
    Location:16 → 74
    Ig; Immunoglobulin domain
    cl14633
    Location:680 → 762
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

    Range
    21584814..21936742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038582098.1 → XP_038438026.1  netrin receptor UNC5C isoform X1

    UniProtKB/TrEMBL
    A0A8C0JQH3, A0A8I3PF54, A0A8I3PFL2
    Conserved Domains (6) summary
    smart00218
    Location:547 → 650
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:697 → 836
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:863 → 945
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_038582099.1 → XP_038438027.1  netrin receptor UNC5C isoform X2

    UniProtKB/TrEMBL
    A0A8C0JT61, A0A8I3PFL2, A0A8I3S2Y3
    Conserved Domains (6) summary
    smart00218
    Location:528 → 631
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:678 → 817
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:844 → 926
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_038582100.1 → XP_038438028.1  netrin receptor UNC5C isoform X3

    UniProtKB/TrEMBL
    A0A8C0JU44
    Conserved Domains (6) summary
    smart00218
    Location:364 → 467
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:80 → 131
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:514 → 653
    UPA; UPA domain
    cd00096
    Location:16 → 20
    Ig; Ig strand C [structural motif]
    cl11960
    Location:16 → 74
    Ig; Immunoglobulin domain
    cl14633
    Location:680 → 762
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23609404..23959891
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005639213.4 → XP_005639270.1  netrin receptor UNC5C isoform X1

    UniProtKB/TrEMBL
    A0A8C0JQH3, A0A8I3PF54, A0A8I3PFL2
    Conserved Domains (6) summary
    smart00218
    Location:547 → 650
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:697 → 836
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:863 → 945
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_856786.6 → XP_861879.1  netrin receptor UNC5C isoform X2

    UniProtKB/TrEMBL
    A0A8C0JT61, A0A8I3PFL2, A0A8I3S2Y3
    Conserved Domains (6) summary
    smart00218
    Location:528 → 631
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:263 → 314
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:678 → 817
    UPA; UPA domain
    cd00096
    Location:175 → 179
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:171 → 257
    Ig; Immunoglobulin domain
    cl14633
    Location:844 → 926
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_022413547.2 → XP_022269255.1  netrin receptor UNC5C isoform X3

    UniProtKB/TrEMBL
    A0A8C0JU44
    Conserved Domains (6) summary
    smart00218
    Location:364 → 467
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00209
    Location:80 → 131
    TSP1; Thrombospondin type 1 repeats
    pfam17217
    Location:514 → 653
    UPA; UPA domain
    cd00096
    Location:16 → 20
    Ig; Ig strand C [structural motif]
    cl11960
    Location:16 → 74
    Ig; Immunoglobulin domain
    cl14633
    Location:680 → 762
    DD; Death Domain Superfamily of protein-protein interaction domains
Nucleotide Protein
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