MAP2K1 mitogen-activated protein kinase kinase 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: MAP2K1provided by VGNC
Official Full Name: mitogen-activated protein kinase kinase 1provided by VGNC
Primary source: VGNC:VGNC:42960
See related: Ensembl:ENSCAFG00845015371 RGD:12140765
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: all
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Genomic context

Location:: chromosome: 30

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	30	NC_051834.1 (30879701..30957083)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	30	NC_006612.4 (30613296..30690593)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	30	NC_049251.1 (31110222..31187514)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	30	NC_049290.1 (30809219..30886485)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	30	NC_049771.1 (30868842..30945867)

Chromosome 30 - NC_051834.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MAP2K1 (e-PCR)
- UniSTS:503136

RH68988 (e-PCR)
- UniSTS:89532

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity mitogen-activated protein kinase kinase 1

Names: dual specificity mitogen activated protein kinase kinase 1

NP_001041559.2

EC 2.7.12.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001048094.2 → NP_001041559.2 dual specificity mitogen-activated protein kinase kinase 1

Status: VALIDATED

Source sequence(s)

JAAUVH010000365

UniProtKB/TrEMBL

A0A8C0QXB7, A0A8I3NMM5

Related

ENSCAFP00845021698.1, ENSCAFT00845027576.1

Conserved Domains (1) summary

cd06650
Location:62 → 380

PKc_MEK1; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase 1